蓖麻毒素——一种强大的蛋白质合成抑制剂。 - Suppr

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超能文献

Ricin - a potent inhibitor of protein synthesis.

作者信息

Olsnes S, Pihl A

机构信息

Norsk Hydro's Institute for Cancer Research, The Norwegian Radium Hospital, Montebello, 3, Oslo, Norway

出版信息

FEBS Lett. 1972 Feb 15;20(3):327-329. doi: 10.1016/0014-5793(72)80098-x.

DOI:10.1016/0014-5793(72)80098-x

PMID:11946449

Abstract

摘要

相似文献

Ricin - a potent inhibitor of protein synthesis.蓖麻毒素——一种强大的蛋白质合成抑制剂。

FEBS Lett. 1972 Feb 15;20(3):327-329. doi: 10.1016/0014-5793(72)80098-x.

The X-ray structure of ricin A chain with a novel inhibitor.带有新型抑制剂的蓖麻毒素A链的X射线结构

Arch Biochem Biophys. 2009 Mar 1;483(1):23-8. doi: 10.1016/j.abb.2008.12.013. Epub 2008 Dec 30.

Cross-talk between the pathways leading to the induction of apoptosis and the secretion of tumor necrosis factor-alpha in ricin-treated RAW 264.7 cells.蓖麻毒素处理的RAW 264.7细胞中诱导凋亡途径与肿瘤坏死因子-α分泌之间的相互作用。

J Biochem. 2003 Dec;134(6):927-33. doi: 10.1093/jb/mvg224.

Selective destruction of nerve growth factor receptor-bearing cells in vitro using a hybrid toxin composed of ricin A chain and a monoclonal antibody against the nerve growth factor receptor.利用由蓖麻毒素A链和抗神经生长因子受体单克隆抗体组成的杂合毒素在体外对携带神经生长因子受体的细胞进行选择性破坏。

J Cell Biol. 1985 Sep;101(3):1107-14. doi: 10.1083/jcb.101.3.1107.

Ricin-mediated cell-lysis and apoptosis of drug sensitive and resistant tumor-cells.

Int J Oncol. 1993 Mar;2(3):363-71.

Dual effects of the ricin A chain on protein synthesis in rabbit reticulocyte lysate. Inhibition of initiation and translocation.蓖麻毒素A链对兔网织红细胞裂解物中蛋白质合成的双重作用。对起始和转位的抑制。

Eur J Biochem. 1990 Oct 24;193(2):401-7. doi: 10.1111/j.1432-1033.1990.tb19353.x.

Anti-Thy 1.2 monoclonal antibody linked to ricin is a potent cell-type-specific toxin.与蓖麻毒素连接的抗Thy 1.2单克隆抗体是一种有效的细胞类型特异性毒素。

Proc Natl Acad Sci U S A. 1980 Sep;77(9):5483-6. doi: 10.1073/pnas.77.9.5483.

Enhancement of the cytotoxicity of liposomal ricin by the carboxylic ionophore monensin and the lysosomotropic amine NH4Cl in Chinese hamster ovary cells.羧酸离子载体莫能菌素和溶酶体促渗胺氯化铵增强脂质体蓖麻毒素对中国仓鼠卵巢细胞的细胞毒性作用

Int J Toxicol. 2006 Sep-Oct;25(5):349-59. doi: 10.1080/10915810600846195.

Evaluation of ricin A chain-containing immunotoxins directed against CD19 and CD22 antigens on normal and malignant human B-cells as potential reagents for in vivo therapy.评估针对正常和恶性人B细胞上CD19和CD22抗原的含蓖麻毒素A链免疫毒素作为体内治疗潜在试剂的效果。

Cancer Res. 1988 May 1;48(9):2610-7.

Polyclonal anti-idiotypes induce antibody responses protective against ricin cytotoxicity.多克隆抗独特型抗体可诱导产生对蓖麻毒素细胞毒性具有保护作用的抗体反应。

Immunology. 1993 Aug;79(4):681-4.

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Medical Countermeasures against Ricin Intoxication.抗蓖麻毒素医疗对策。

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Targeting the Inside of Cells with Biologicals: Toxin Routes in a Therapeutic Context.靶向细胞内的生物制品：治疗环境中的毒素途径。

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Ribotoxic Proteins, Known as Inhibitors of Protein Synthesis, from Mushrooms and Other Fungi According to Endo's Fragment Detection.根据 Endo 的片段检测，来自蘑菇和其他真菌的核糖毒性蛋白，被称为蛋白质合成抑制剂。

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Intracellular Transport and Cytotoxicity of the Protein Toxin Ricin.细胞内转运和蛋白毒素蓖麻毒素的细胞毒性。

Toxins (Basel). 2019 Jun 18;11(6):350. doi: 10.3390/toxins11060350.

Ricin: An Ancient Story for a Timeless Plant Toxin.蓖麻毒素：古老的故事，永恒的植物毒素。

Toxins (Basel). 2019 Jun 6;11(6):324. doi: 10.3390/toxins11060324.

How Ricin Damages the Ribosome.蓖麻毒素如何损伤核糖体。

Toxins (Basel). 2019 Apr 27;11(5):241. doi: 10.3390/toxins11050241.

Functional Assays for Measuring the Catalytic Activity of Ribosome Inactivating Proteins.用于测量核糖体失活蛋白催化活性的功能测定法。

Toxins (Basel). 2018 Jun 14;10(6):240. doi: 10.3390/toxins10060240.

Extensive Evolution of Cereal Ribosome-Inactivating Proteins Translates into Unique Structural Features, Activation Mechanisms, and Physiological Roles.谷物核糖体失活蛋白的广泛进化转化为独特的结构特征、激活机制和生理作用。

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