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前庭分析仪作为评估太空飞行期间辐射危害的关键器官。

Vestibular analyzer as a critical organ in the evaluation of radiation hazards during space flights.

作者信息

Grigoryev Y G

机构信息

USSR.

出版信息

Life Sci Space Res. 1969;7:173-85.

PMID:11949686
Abstract

During space flights the vestibular analyzer functions under conditions which are not usual for Earth environments. The vestibular analyzer periodically or constantly experiences the action of angular, linear or Coriolis acceleration combined with ionizing radiation. The quantitative evaluation of the functional state of the vestibular analyzer made it possible to obtain material on semicircular canal activity disturbances at different periods of radiation sickness and responses of the irradiated body, given various doses of gamma radiation, to angular and Coriolis acceleration. Experiments were performed on 250 rabbits and 22 dogs. Rabbits were exposed to the total gamma radiation at doses of 50, 100, 500, 800, 5000, 10000 rad; dogs experienced single and fractional radiation exposures at doses of 200 rad (gamma-rays) and at doses of 500 and 350 rad (protons of 510 MeV). Specific conditions under which the astronaut's vestibular analyzer is functioning during space missions and our own experimental results make it possible to state that the vestibular analyzer serves as the critical organ in evaluation of radiation hazards during space flights.

摘要

在太空飞行期间,前庭分析器在不同于地球环境的条件下发挥功能。前庭分析器会周期性地或持续地受到角加速度、线加速度或科里奥利加速度的作用,同时还会受到电离辐射。对前庭分析器功能状态的定量评估,使得获取有关不同辐射病阶段半规管活动障碍以及在不同剂量伽马辐射下受辐照机体对角加速度和科里奥利加速度反应的资料成为可能。实验是在250只兔子和22只狗身上进行的。兔子接受了剂量为50、100、500、800、5000、10000拉德的全身伽马辐射;狗接受了单次和分次辐射照射,剂量分别为200拉德(伽马射线)以及500和350拉德(510兆电子伏的质子)。宇航员前庭分析器在太空任务期间发挥功能的特定条件以及我们自己的实验结果表明,前庭分析器是评估太空飞行期间辐射危害的关键器官。

相似文献

1
Vestibular analyzer as a critical organ in the evaluation of radiation hazards during space flights.前庭分析仪作为评估太空飞行期间辐射危害的关键器官。
Life Sci Space Res. 1969;7:173-85.
2
[Vestibular analysor--a critical organ for the evaluation of radiation hazards in space flights. (Effect of a wide-dosage-range ionizing radiation on the physiological functions of the cupular apparatus)].[前庭分析器——太空飞行中辐射危害评估的关键器官。(宽剂量范围电离辐射对壶腹器官生理功能的影响)]
Physiol Bohemoslov. 1966;15(4):372-7.
3
[Effect of radiation-protective agents on the functional state of the vestibular analyzer].[辐射防护剂对前庭分析器功能状态的影响]
Kosm Biol Med. 1973 Mar-Apr;7(2):45-8.
4
Vestibular nystagmus under hyperbaric conditions.
Biol Bull Acad Sci USSR. 1979 Jul-Aug;6(4):405-10.
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[The effect of the radiosensitivity of an organism on the nature of functional changes in the vestibular analyzer following subjection to ionizing radiation].[机体放射敏感性对电离辐射作用后前庭分析器功能变化性质的影响]
Biull Eksp Biol Med. 1968 Apr;65(4):51-3.
6
[A biophysical analysis of the effect of Coriolis accelerations on the vestibular analyzer].[科里奥利加速度对前庭分析仪影响的生物物理分析]
Izv Akad Nauk SSSR Biol. 1976 May-Jun(3):449-52.
7
[Initial reactions of the vestibular analyzer of rabbits to local irradiation].[家兔前庭分析器对局部照射的初始反应]
Radiobiologiia. 1967 May-Jun;7(3):429-32.
8
[Combined effect of acceleration and ionizing radiation on higher nervous activity and the functional state of the vestibular analyzer].[加速度与电离辐射对高级神经活动及前庭分析器功能状态的联合作用]
Radiobiologiia. 1969 Jan-Feb;9(1):46-51.
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[Relation between the state of the vestibular analyzer in rabbits and their individual radiosensitivity when irradiated with a dose of 150 Gy].[150戈瑞剂量照射下家兔前庭分析器状态与其个体辐射敏感性之间的关系]
Radiobiologiia. 1983 Jul-Aug;23(4):549-51.
10
[Functional condition of the visual and vestibular analyzers in workers exposed to small doses of ionizing radiation].[小剂量电离辐射暴露工人视觉和前庭分析器的功能状况]
Gig Tr Prof Zabol. 1970 Sep;14(9):44-6.