Yang Zhiying, Zhao Ping, Liu Zhan, Tang Weisong, Zhong Shouxian
Department of General Surgery, Peking Union Medical College Hospital, Beijing 100730, China.
Zhonghua Yi Xue Za Zhi. 2002 Mar 25;82(6):376-8.
To summarize the clinical aspects of nonfunctional islet-cell tumor (NIT) reported in Chinese periodicals.
Articles in Chinese on NIT were screened from the Chinese Bio-Medical Database (1981.1 - 1999.10). Data of epidemiology, clinical manifestations, diagnosis, defferential diagnosis, and treatment of NIT were analyzed.
60 articles and 237 cases of NIT were selected. The female to male ratio was 2.9:1. Abdominal mass was the most common clinical symptom. It was difficult for the pre-operative diagnosis of NIT and differentiation from pancreatic tumor or retroperitoneal mass. The malignant rate of NIT was 35%. The five-year survival rate of malignant NIT was 53.1%.
NIT is rare. It occurs more often in female than in male. The preoperative diagnostic rate is rather low. The prognosis of malignant NIT is favorable. Active treatment is strongly recommended.
总结中文期刊报道的无功能性胰岛细胞瘤（NIT）的临床特点。
从中国生物医学数据库（1981.1 - 1999.10）中筛选有关NIT的中文文章。分析NIT的流行病学、临床表现、诊断、鉴别诊断及治疗等资料。
选取60篇文章共237例NIT。男女比例为1:2.9。腹部肿块是最常见的临床症状。NIT术前诊断困难，难以与胰腺肿瘤或腹膜后肿块相鉴别。NIT的恶性率为35%。恶性NIT的5年生存率为53.1%。
NIT罕见，女性多于男性，术前诊断率较低，恶性NIT预后良好，强烈建议积极治疗。
