Merrin C, Cartagena R, Wajsman Z, Baumgartner G, Murphy G P
J Urol. 1975 Dec;114(6):884-7. doi: 10.1016/s0022-5347(17)67165-9.
We assigned 49 patients with transitional cell carcinoma of the bladder to 1 of 3 groups: 21 patients (group 1) received cyclophosphamide alone, 10 patients (group 2) received adriamycin alone and 18 patients (group 3) received cyclophosphamide and adriamycin. The objective responses were 52.3 per cent in group 1, 10 per cent in group 2 and 50 per cent in group 3. These results suggest a significant activity of the drugs (especially in groups 1 and 3) tested in bladder cancer.
我们将49例膀胱移行细胞癌患者分为3组中的1组：21例患者（第1组）仅接受环磷酰胺治疗，10例患者（第2组）仅接受阿霉素治疗，18例患者（第3组）接受环磷酰胺和阿霉素治疗。第1组的客观缓解率为52.3%，第2组为10%，第3组为50%。这些结果表明所测试的药物（尤其是第1组和第3组中的药物）在膀胱癌中具有显著活性。
