Hoffmann Esther, Schwenn Oliver, Karallus Matthias, Krummenauer Frank, Grehn Franz, Pfeiffer Norbert
Department of Ophthalmology, Johannes Gutenberg University of Mainz, Germany.
Graefes Arch Clin Exp Ophthalmol. 2002 Jan;240(1):2-6. doi: 10.1007/s004170100337.
There are different surgical approaches for cataract and concomitant primary open-angle glaucoma (POAG). In a retrospective study we examined the long-term results of cataract extraction combined with trabeculotomy.
Between 1990 and 1997, 194 eyes with cataract and POAG were operated on in a combined manner. Eighty-eight eyes received a trabeculotomy (TT), in 82 eyes a trabeculectomy was added to the trabeculotomy (TT+TE) and in 24 eyes, in which probing of Schlemm's canal was impossible, standard trabeculectomy (TE) was performed. Pre- and postoperative intraocular pressure (IOP), glaucoma medication, and the intra- and postoperative complications of all patients were analyzed.
Hyphema was the most common complication in the TT group (20.5%). Fibrin reaction occurred in 27.8% of all cases. There was no statistically significant difference in postoperative IOP between the TT group and the TT+TE group. A statistically significant decrease in IOP compared to preoperatively lasted 60 months in the TT group. In eyes with a preoperative IOP < or = 20 mmHg, none of the three procedures reduced IOP significantly (<20% of the preoperative IOP). In the first 2 years after operation 50% of the patients had no need for antiglaucomatous medication.
Cataract surgery combined with TT resulted in few complications. In low-tension glaucoma the combination with TT is not sufficient to decrease the IOP. In patients with higher preoperative IOP, however, cataract surgery combined with TT could be--on the basis of a postoperative observation time of 72 months--a suitable method for lowering the IOP sufficiently. Furthermore, the use of antiglaucomatous substances was reduced by this combined procedure.
白内障合并原发性开角型青光眼(POAG)有不同的手术方法。在一项回顾性研究中,我们检查了白内障摘除联合小梁切开术的长期效果。
1990年至1997年间,194例白内障合并POAG患者接受了联合手术。88只眼接受了小梁切开术(TT),82只眼在小梁切开术基础上加做了小梁切除术(TT+TE),24只因无法探查施莱姆管而进行了标准小梁切除术(TE)。分析了所有患者术前和术后的眼压(IOP)、青光眼用药情况以及手术中和术后并发症。
前房积血是TT组最常见的并发症(20.5%)。所有病例中有27.8%发生纤维蛋白反应。TT组与TT+TE组术后眼压无统计学显著差异。TT组眼压较术前有统计学显著下降持续了60个月。术前眼压≤20 mmHg的眼中,三种手术方法均未显著降低眼压(<术前眼压的20%)。术后头2年,50%的患者无需使用抗青光眼药物。
白内障手术联合TT并发症较少。在低眼压性青光眼中,联合TT不足以降低眼压。然而,对于术前眼压较高的患者,基于72个月的术后观察时间,白内障手术联合TT可能是充分降低眼压的合适方法。此外,这种联合手术减少了抗青光眼药物的使用。