Ogretmenoglu Oguz, Yilmaz Taner, Rahimi Keikavos, Aksöyek Serdar
Hacettepe University, Faculty of Medicine, Department of Otolaryngology-Head and Neck Surgery, Bahçelievler Ankara, Turkey.
Eur Arch Otorhinolaryngol. 2002 Feb;259(2):63-6. doi: 10.1007/s00405-001-0422-1.
In order to elucidate the blood gas and heart rate changes caused by bilateral nasal packing, 21 healthy subjects who had had septoplasty or septorhinoplasty were investigated with pre- and post-operative blood gas measurements and 24-h Holter monitoring. Nasal packing caused a significant decrease in O2 saturation (P < 0.05), a borderline decrease in PO2 (P = 0.09), insignificant changes in PCO2, pH and HCO3 (P > 0.05), a significant increase in minimum and mean heart rates (P < 0.05) and insignificant changes in maximum heart rates; however, further research is necessary to elucidate the direct cause-and-effect relationship. No serious arrhythmias were observed. Although these changes may be within normal levels for healthy subjects, they may have serious consequences for patients with cardiopulmonary diseases.
为了阐明双侧鼻腔填塞引起的血气和心率变化，对21例接受过鼻中隔成形术或鼻整形术的健康受试者进行了术前和术后血气测量以及24小时动态心电图监测。鼻腔填塞导致氧饱和度显著下降（P < 0.05），动脉血氧分压呈临界下降（P = 0.09），二氧化碳分压、pH值和碳酸氢根无显著变化（P > 0.05），最低和平均心率显著增加（P < 0.05），最高心率无显著变化；然而，需要进一步研究以阐明直接的因果关系。未观察到严重心律失常。尽管这些变化对于健康受试者可能处于正常水平，但对于患有心肺疾病的患者可能会产生严重后果。
