Joseph Peter, Mandal A K, Singh S K, Mandal Purabi, Sankhwar S N, Sharma S K
Department of Urology, Postgraduate Institute of Medical Education and Research, and MRI and CT Scan Centre, Chandigarh, India.
J Urol. 2002 May;167(5):1968-71. doi: 10.1016/s0022-5347(05)65064-1.
We evaluated the attenuation value of renal calculi on unenhanced axial computerized tomography (CT) images as a predictor of calculous fragmentation by extracorporeal shockwave lithotripsy (ESWL) (Dornier Medical Systems, Inc., Marietta, Georgia).
We included 30 patients with renal calculi up to 20 mm. in this prospective study. Calculous attenuation value was measured in Hounsfield units on unenhanced CT sections through the calculi. Patients were subsequently treated with ESWL.
Patients were grouped according to calculous attenuation value as groups 1-less than 500, 2-500 to 1,000 and 3-greater than 1,000 Hounsfield units. Of the 30 patients 24 (80%) underwent successful treatment. The rate of stone clearance was 100% (12 of 12 cases) in group 1, 85.7% (6 of 7) in group 2 and 54.5% (6 of 11) in group 3. The success rate for stones with an attenuation value of greater than 1,000 Hounsfield units was significantly lower than that for stones with a value of less than 1,000 Hounsfield units (6 of 11 versus 18 of 19 cases, chi-square 7.07, p <0.01). Patients in group 3 required a greater median number of shock waves for stone fragmentation than those in groups 1 and 2 (7,300, 2,500, and 3,390, respectively). The mean attenuation value and number of shock waves required for calculous fragmentation correlated significantly (r = 0.779, p <0.001).
The CT attenuation value of renal calculi can help to differentiate stones that are likely to fragment easily on ESWL from those that would require a greater number of shock waves for fragmentation or may fail to fragment on ESWL.
我们评估了未增强轴向计算机断层扫描(CT)图像上肾结石的衰减值,以预测体外冲击波碎石术(ESWL)(多尼尔医疗系统公司,佐治亚州玛丽埃塔)对结石的破碎效果。
在这项前瞻性研究中,我们纳入了30例结石最大直径达20mm的肾结石患者。通过结石的未增强CT断层扫描,以亨氏单位测量结石的衰减值。随后患者接受ESWL治疗。
根据结石衰减值将患者分为三组:1组衰减值小于500亨氏单位,2组衰减值为500至1000亨氏单位,3组衰减值大于1000亨氏单位。30例患者中,24例(80%)治疗成功。1组结石清除率为100%(12例中的12例),2组为85.7%(7例中的6例),3组为54.5%(11例中的6例)。衰减值大于1000亨氏单位的结石成功率显著低于衰减值小于1000亨氏单位的结石(11例中的6例对19例中的18例,卡方值7.07,p<0.01)。3组患者结石破碎所需的冲击波中位数比1组和2组更多(分别为7300、2500和3390)。结石破碎所需的平均衰减值与冲击波数量显著相关(r = 0.779,p<0.001)。
肾结石的CT衰减值有助于区分ESWL时易于破碎的结石与需要更多冲击波才能破碎或ESWL可能无法破碎的结石。