Horn Charles C, Kupfermann Irving
Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104, USA.
Neurosci Lett. 2002 May 3;323(3):175-8. doi: 10.1016/s0304-3940(02)00155-6.
Ingestive and egestive behaviors in Aplysia are generated by motor neurons and interneurons chiefly located in the buccal ganglion, but cerebral ganglion neurons appear to contribute to both ingestive and egestive motor programs. We investigated if the cerebral ganglion input to the buccal ganglion is necessary for the generation of buccal ingestive and egestive behaviors in free-moving animals. We confirmed a prior study that showed that animals with lesions of the cerebro-buccal connectives (CBCs) do not exhibit rhythmic biting following seaweed stimulation of the lips, but do show swallowing of seaweed inserted into the buccal cavity. We found that CBC-lesioned animals also exhibited rejection of a tube inserted into the buccal cavity and esophagus. The programs for swallowing and rejection behaviors were similar to those observed before lesioning the CBCs, although the rate of swallowing was slower. These results suggest that the cerebral input to the buccal ganglion is necessary for generating biting responses, but is not required for producing swallowing or rejection responses.
海兔的摄食和排粪行为由主要位于口神经节的运动神经元和中间神经元产生，但脑神经元似乎也参与了摄食和排粪运动程序。我们研究了在自由活动的动物中，脑神经元对口神经节的输入对于口部摄食和排粪行为的产生是否必要。我们证实了之前的一项研究，该研究表明，脑-口连接（CBCs）受损的动物在嘴唇受到海藻刺激时不会表现出有节奏的咬食，但会表现出吞咽插入口腔的海藻。我们发现，CBC受损的动物也会排斥插入口腔和食管的管子。吞咽和排斥行为的程序与损伤CBC之前观察到的相似，尽管吞咽速度较慢。这些结果表明，脑对口神经节的输入对于产生咬食反应是必要的，但对于产生吞咽或排斥反应则不是必需的。
