[外分泌腺泡细胞中钙信号产生的机制]
[Mechanisms of generating calcium signals in exocrine acinar cells].
作者信息
Shevchuk P M, Rybal'chenko V K
机构信息
Research Institute of Physiology, Taras Shevchenko Kiev University, Kiev.
出版信息
Fiziol Zh (1994). 2001;47(6):85-96.
PMID:11962097
Abstract
Review. Modern data about mechanisms of generation of the calcium signals in the exocrine acinar cells are presented. The mechanisms of inositol-1,4,5-trisphosphate- and Ca(2+)-induced Ca2+ release from intracellular stores of the acinar cells and mechanisms their influx from extracellular medium are described. The mechanisms which initiate Ca2+ oscillations and their role in the secretion of the fluid and enzymes by acinar cells are discussed.
摘要
综述。本文介绍了有关外分泌腺泡细胞中钙信号产生机制的现代数据。描述了肌醇-1,4,5-三磷酸和Ca(2+)诱导腺泡细胞细胞内储存库释放Ca2+的机制及其从细胞外介质流入的机制。讨论了引发Ca2+振荡的机制及其在腺泡细胞分泌液体和酶中的作用。
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