Kato Noriko, Akiyama Sunao, Motoyama Teiichi
Department of Pathology, Yamagata University School of Medecine, Yamagata, 990-9585, Japan, Japan.
Virchows Arch. 2002 Feb;440(2):205-208. doi: 10.1007/s004280100535.
We report a rare case of pyloric gland-type tubular adenoma of the main pancreatic duct. It was a grossly visible polypoid nodule and was composed of closely packed pyloric-type glands. This adenoma was present within an intraductal papillary mucinous adenoma (IPMA). In this IPMA lesion, aggregations of pyloric-type glands were occasionally observed, and most of the cells including ductal lining cells expressed pyloric gland-type mucin. The IPMA of the present case showed more extensive pyloric gland metaplasia or differentiation than commonly noted in IPMAs. We consider this pyloric gland-type tubular adenoma to be derived from a selective growth of IPMA cells showing pyloric gland metaplasia.
我们报告一例主胰管幽门腺型管状腺瘤的罕见病例。它是一个肉眼可见的息肉样结节，由紧密排列的幽门型腺体组成。该腺瘤存在于导管内乳头状黏液性腺瘤（IPMA）中。在这个IPMA病变中，偶尔观察到幽门型腺体聚集，并且包括导管内衬细胞在内的大多数细胞表达幽门腺型黏蛋白。本病例的IPMA显示出比IPMA中常见情况更广泛的幽门腺化生或分化。我们认为这种幽门腺型管状腺瘤源自显示幽门腺化生的IPMA细胞的选择性生长。
