Arrada A, Zak Dit Zbar O, Vasseur V
Unité de Consultations et de Soins Ambulatoires, Hôpital Cochin, Maison d'Arrêt de Paris, La Santé, France.
Ann Med Interne (Paris). 2001 Nov;152 Suppl 7:6-8.
The concentration of a marginal population (35% drug addicts) in prisons necessitates systematic and rigorous screening for hepatitis B and hepatitis C in subjects at risk. In June 1998, a screening program was initiated to determine the prevalence of HBV and HBC infections in prisoners and to determine the incidence after 3, 6 and 12 months detention. The screening program was proposed to 900 prisoners in a Paris prison (Maison d'arrêt de Paris-La Santé) from June 3 to November 10, 1998. The program included hepatitis B and hepatitis C serology at incarceration. For prisoners who were seronegative for HCV at incarceration, a new HCV serology was proposed after 3, 6 and 12 months detention. It was postulated that HCV contamination could occur during incarceration (syringe sharing, tattooing). After one year of incarceration, no seroconversions for HCV were observed among the prisoners participating in this study. These findings should be interpreted with caution due to the particular detention conditions at the prison involved, raising important methodology interrogations concerning this type of survey.
监狱中边缘人群(35%为吸毒者)的集中使得有必要对高危人群进行系统且严格的乙肝和丙肝筛查。1998年6月,启动了一项筛查计划,以确定囚犯中乙肝病毒(HBV)和丙肝病毒(HBC)感染的患病率,并确定拘留3个月、6个月和12个月后的发病率。1998年6月3日至11月10日,该筛查计划在巴黎一所监狱(巴黎-拉桑泰拘留所)的900名囚犯中展开。该计划包括入狱时的乙肝和丙肝血清学检测。对于入狱时丙肝病毒血清学检测呈阴性的囚犯,在拘留3个月、6个月和12个月后再次进行丙肝病毒血清学检测。据推测,丙肝病毒感染可能在监禁期间发生(共用注射器、纹身)。在参与本研究的囚犯中,监禁一年后未观察到丙肝病毒血清学转换。由于所涉监狱的特殊拘留条件,这些结果应谨慎解读,这引发了关于此类调查的重要方法学问题。