[二氧化碳激光经口显微手术治疗原位声门癌]
[Carbon dioxide laser transoral microsurgery for glottic carcinoma in situ].
作者信息
De Monès E, Hans S, Hartl D M, Laccourreye O, Brasnu D
机构信息
Service d'otorhinolaryngologie et de chirurgie de la face et du cou, Hôpital Européen Georges Pompidou, Université Paris V, 20 rue Leblanc. 75015 Paris.
出版信息
Ann Otolaryngol Chir Cervicofac. 2002 Feb;119(1):21-30.
OBJECTIVE
To evaluate the oncologic results of glottic carcinoma in situ (CIS) treated with transoral carbon dioxide laser microsurgery.
METHODS
A retrospective review of 12 patients with glottic CIS previously untreated, treated with carbon dioxide laser transoral microsurgery between January 1990 and December 1999 was conducted.
RESULTS
Initial and ultimate local control rates were 75%, and 100%, respectively. Three local failures occurred: two glottic CIS were treated by carbon dioxide laser transoral microsurgery, one squamous cell glottic carcinoma was treated by supracricoid partial laryngectomy with cricohyoidoepiglottopexy. The ultimate rate of laryngeal preservation rate was 100%.
CONCLUSIONS
Based on the material of this study, recommended treatment for glottic CIS should be carbon dioxide laser transoral microsurgery. Difficulties in endoscopic exposure of the larynx is a contraindication. Further studies are necessary to confirm these preliminary results.
目的
评估经口二氧化碳激光显微手术治疗原位声门癌（CIS）的肿瘤学疗效。
方法
对1990年1月至1999年12月间12例未经治疗的原位声门癌患者进行回顾性研究，这些患者均接受了经口二氧化碳激光显微手术治疗。
结果
初始局部控制率和最终局部控制率分别为75%和100%。发生了3例局部复发：2例原位声门癌接受了经口二氧化碳激光显微手术治疗，1例声门鳞状细胞癌接受了环状软骨上部分喉切除术加环舌会厌固定术。最终喉保留率为100%。
结论
基于本研究资料，原位声门癌的推荐治疗方法应为经口二氧化碳激光显微手术。内镜下暴露喉部困难是其禁忌证。需要进一步研究以证实这些初步结果。
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