[使用相控阵磁共振成像对前列腺癌进行局部分期：5年的前瞻性研究]
[Local staging of prostate carcinoma with phased array MR imaging: prospective study over 5 years].
作者信息
Aziza R, Soulié M, Escourrou G, Bachaud Jm, Molinié L, Tollon C, Joffre F, Plante P
机构信息
Institut Claudius Regaud. 20, rue du Pont Saint Pierre, 31052 Toulouse, France.
出版信息
J Radiol. 2002 Jan;83(1):39-44.
PURPOSE
To assess by MRI, using a pelvic phased array coil, the accuracy for staging prostate carcinoma and to correlate the results with the rate of positive surgical margins.
MATERIALS AND METHODS
Between January 1995 and December 1999, 176 patients with localized prostate carcinoma underwent a preoperative MRI examination using a pelvic phased-array coil (1 Tesla). MRI and histological results were compared in a prospective study.
RESULTS
131 were classified T2 and 45 were classified T3 at MRI. Pathologic findings showed 103 pT2 and 73 pT3. The accuracy of MRI (extra capsular or vesicle extension) was 75%. The risk for a patient labelled T2 or T3 at MRI to have a positive surgical margin was respectively 13.7% and 31%.
CONCLUSION
This study shows that the phased-array coil has a low sensitivity but a good specificity to distinguish between organ-confined cancer or not. It shows that the risk of positive surgical margins is higher for T3 lesions at MRI. The low sensitivity should be improved by using a multi coil phased array.
目的
使用盆腔相控阵线圈通过磁共振成像（MRI）评估前列腺癌分期的准确性，并将结果与手术切缘阳性率相关联。
材料与方法
1995年1月至1999年12月期间，176例局限性前列腺癌患者使用盆腔相控阵线圈（1特斯拉）进行了术前MRI检查。在一项前瞻性研究中对MRI和组织学结果进行了比较。
结果
MRI检查显示131例为T2期，45例为T3期。病理结果显示103例为pT2期，73例为pT3期。MRI（包膜外或精囊侵犯）的准确率为75%。MRI检查标记为T2或T3的患者手术切缘阳性的风险分别为13.7%和31%。
结论
本研究表明，相控阵线圈区分局限于器官内的癌症的敏感性较低，但特异性较好。研究表明，MRI检查为T3期病变的患者手术切缘阳性的风险较高。应通过使用多线圈相控阵来提高低敏感性。
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