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[连续头高位倾斜试验期间心率、血压、心率变异性和脑血流的特征]

[Features of heart rate, blood pressure, heart rate variability and cerebral blood flow during sequential head-up tilt test].

作者信息

Wu Liu-xin, Qiang Dong-chang, Song Lei, Shi Lu-jiang, Zheng Xue-wei, Jiao Zhi-gang

机构信息

Institute of Aviation Medicine, Beijing, China.

出版信息

Space Med Med Eng (Beijing). 2002 Feb;15(1):22-6.

Abstract

OBJECTIVE

To investigate the features of BP, HR, cerebral blood flow (CBF) and heart rate variation (HRV) during sequential head-up tilt table test (HUT) and provide information for methodology of testing tendency to syncope in pilots.

METHOD

Sixteen healthy male were exposed to HUT +45 degrees 20 min, +60 degrees 20 min, and +75 degrees 20 min respectively with 5 min rests in between. CBFV, HR, HRV, BP were measured with transcranial doppler image (TCI), 12-Lead in phase ECG.

RESULT

  1. As the tilt angle became larger, HR and DBP increased gradually (P<0.05), with SBP, PP and CBF Velocity (Vs,Vm,Vd) descended. There were significant differences among the various conditions. CV became smaller before +75 degrees, and then it began to increase. 2) Correlation between physiological indices and techno-indices were analyzed. At the point of 1 min, tilt angle was significantly positively correlated with SBP, DBP, MAP, Vd, and sdRR (P<0.01); At the point of 20 min, tilt angle was significantly positively correlated with HR and sdRR (P<0.01), but negatively correlated with SBP, PP, Vs and mRR (P<0.01), time of exposure was positively correlated with HP (P< 0.01), but negatively correlated with Vm, Vd, and mRR (P<0.01). 3) Correlation among physiological indices were also analyzed. HR were negatively correlated with SBP, Vs, Vm and Vd (P<0.01), SBP were significantly positively correlated with Vd, and mRR (P<0.01). Vs, Vm, Vd were significantly positively correlated with mRR and sdRR (P< 0.01).

CONCLUSION

By investigating HR, BP, HRV and CBFV during of different angles, some advises for evaluating the tendency to syncope in pilots were put forward.

摘要

目的

探讨连续头高位倾斜试验(HUT)过程中血压(BP)、心率(HR)、脑血流量(CBF)和心率变异性(HRV)的特征,为飞行员晕厥倾向测试方法提供依据。

方法

16名健康男性分别进行+45度倾斜20分钟、+60度倾斜20分钟和+75度倾斜20分钟的HUT试验,每次倾斜之间休息5分钟。采用经颅多普勒成像(TCI)、12导联同步心电图测量脑血流速度(CBFV)、心率(HR)、心率变异性(HRV)和血压(BP)。

结果

1)随着倾斜角度增大,心率(HR)和舒张压(DBP)逐渐升高(P<0.05),收缩压(SBP)、脉压(PP)和脑血流速度(Vs、Vm、Vd)下降。各条件之间存在显著差异。在+75度之前,变异系数(CV)变小,然后开始增大。2)分析了生理指标与技术指标之间的相关性。在1分钟时倾斜角度与收缩压(SBP)、舒张压(DBP)、平均动脉压(MAP)、Vd和标准差RR(sdRR)显著正相关(P<0.01);在20分钟时倾斜角度与心率(HR)和sdRR显著正相关(P<0.01),但与收缩压(SBP)、脉压(PP)、Vs和平均RR(mRR)负相关(P<0.01),暴露时间与心率(HP)正相关(P<0.01),但与Vm、Vd和mRR负相关(P<0.01)。3)还分析了生理指标之间的相关性。心率(HR)与收缩压(SBP)、Vs、Vm和Vd负相关(P<0.01),收缩压(SBP)与Vd和mRR显著正相关(P<0.01)。Vs、Vm、Vd与mRR和sdRR显著正相关(P<0.01)。

结论

通过研究不同角度下的心率(HR)、血压(BP)、心率变异性(HRV)和脑血流速度(CBFV),对评估飞行员晕厥倾向提出了一些建议。

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