Weedon D, Kerr J F
Pathology. 1975 Jul;7(3):173-7. doi: 10.3109/00313027509094404.
The ultrastructure of two atypical fibroxanthomas of skin is described. Most of the tumour cells were elongate, and contained abundant rough endoplasmic reticulum, well developed Golgi zones, and numerous small vesicles and filaments, the latter sometimes being related to masses of electron-dense material near the plasma-lemma. Their nuclei often showed deep surface indentations. The appearances were similar to those found in the socalled myfibroblasts that occur in granulation tissue. Multinucleated giant cells and lipid-laden cells in the tumours appeared to be merely modified forms of the basic cells type.
本文描述了两例皮肤非典型纤维黄色瘤的超微结构。大多数肿瘤细胞呈细长形，含有丰富的粗面内质网、发育良好的高尔基体区域以及众多小泡和细丝，后者有时与靠近质膜的电子致密物质团块相关。它们的细胞核常呈现出深陷的表面凹陷。这些表现与在肉芽组织中出现的所谓肌成纤维细胞的表现相似。肿瘤中的多核巨细胞和充满脂质的细胞似乎仅仅是基本细胞类型的修饰形式。
