Araki H, Field M, Shwachman H
Pediatr Res. 1975 Dec;9(12):932-4. doi: 10.1203/00006450-197512000-00014.
The in vitro electrical properties of rat jejunum were utilized to assay a factor or factors in serum from patients with cystic fibrosis (CF). Sera from patients with CF were found to decrease short circuit current (SCC) and the SCC response to glucose, and to increase electrical resistance. These effects were present in all 24 patients with CF and 10 of 14 parents of CF patients and absent from the serum of 21 control subjects. This quantitative technique provides an alternative to the ciliostatic assays for the detection of the CF factor or factors.
利用大鼠空肠的体外电特性来检测囊性纤维化（CF）患者血清中的一种或多种因子。发现CF患者的血清会降低短路电流（SCC）以及SCC对葡萄糖的反应，并增加电阻。所有24例CF患者以及14例CF患者父母中的10例的血清都有这些作用，而21名对照受试者的血清中则没有。这种定量技术为检测CF因子提供了一种替代纤毛抑制试验的方法。
