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择期剖宫产、急诊剖宫产或阴道分娩后感染人类免疫缺陷病毒的女性产后发病率差异。

Differences in postpartum morbidity in women who are infected with the human immunodeficiency virus after elective cesarean delivery, emergency cesarean delivery, or vaginal delivery.

作者信息

Marcollet Anne, Goffinet François, Firtion Ghislaine, Pannier Emmanuelle, Le Bret Thiphaine, Brival Marie-Laure, Mandelbrot Laurent

机构信息

Department of Obstetrics and Gynecology, Hôpital Cochin, Paris, France.

出版信息

Am J Obstet Gynecol. 2002 Apr;186(4):784-9. doi: 10.1067/mob.2002.122251.

Abstract

OBJECTIVE

The aim of this study was to assess the impact of elective cesarean delivery on postpartum morbidity in women who are infected with the human immunodeficiency virus (HIV).

STUDY DESIGN

We performed a retrospective study of 401 women who were infected with HIV who were delivered in a single reference center from 1989 through 1999. Women who had cesarean deliveries (n = 201), of which 109 were elective and 92 were emergency, were compared with a group of women who were delivered vaginally (n = 200), composed of the women who were infected with HIV preceding each cesarean delivery.

RESULTS

One or more serious complications occurred after 12% of emergency cesarean deliveries, after 6.4% of elective cesarean deliveries, and after 4% of vaginal deliveries (P =.04). In a multivariate analysis, which was adjusted for maternal CD4 lymphocyte count and antepartum hemorrhage, the relative risk of any postpartum complication (serious or minor) was increased by 1.85 (range, 1.00-3.39) after elective cesarean delivery and 4.17 (range, 2.32-7.49) after emergency cesarean delivery, compared with vaginal deliveries (P =.0001).

CONCLUSION

Postpartum morbidity in women who are infected with HIV was highest after emergency, rather than elective, cesarean deliveries.

摘要

目的

本研究旨在评估择期剖宫产对感染人类免疫缺陷病毒(HIV)女性产后发病率的影响。

研究设计

我们对1989年至1999年在单一参考中心分娩的401例感染HIV的女性进行了一项回顾性研究。将剖宫产的女性(n = 201),其中109例为择期剖宫产,92例为急诊剖宫产,与一组经阴道分娩的女性(n = 200)进行比较,该组由每次剖宫产之前感染HIV的女性组成。

结果

12%的急诊剖宫产、6.4%的择期剖宫产以及4%的阴道分娩后发生了一种或多种严重并发症(P = 0.04)。在对产妇CD4淋巴细胞计数和产前出血进行校正的多变量分析中,与阴道分娩相比,择期剖宫产术后任何产后并发症(严重或轻微)的相对风险增加了1.85(范围为1.00 - 3.39),急诊剖宫产术后增加了4.17(范围为2.32 - 7.49)(P = 0.0001)。

结论

感染HIV的女性产后发病率在急诊剖宫产而非择期剖宫产术后最高。

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