Marcollet Anne, Goffinet François, Firtion Ghislaine, Pannier Emmanuelle, Le Bret Thiphaine, Brival Marie-Laure, Mandelbrot Laurent
Department of Obstetrics and Gynecology, Hôpital Cochin, Paris, France.
Am J Obstet Gynecol. 2002 Apr;186(4):784-9. doi: 10.1067/mob.2002.122251.
The aim of this study was to assess the impact of elective cesarean delivery on postpartum morbidity in women who are infected with the human immunodeficiency virus (HIV).
We performed a retrospective study of 401 women who were infected with HIV who were delivered in a single reference center from 1989 through 1999. Women who had cesarean deliveries (n = 201), of which 109 were elective and 92 were emergency, were compared with a group of women who were delivered vaginally (n = 200), composed of the women who were infected with HIV preceding each cesarean delivery.
One or more serious complications occurred after 12% of emergency cesarean deliveries, after 6.4% of elective cesarean deliveries, and after 4% of vaginal deliveries (P =.04). In a multivariate analysis, which was adjusted for maternal CD4 lymphocyte count and antepartum hemorrhage, the relative risk of any postpartum complication (serious or minor) was increased by 1.85 (range, 1.00-3.39) after elective cesarean delivery and 4.17 (range, 2.32-7.49) after emergency cesarean delivery, compared with vaginal deliveries (P =.0001).
Postpartum morbidity in women who are infected with HIV was highest after emergency, rather than elective, cesarean deliveries.
本研究旨在评估择期剖宫产对感染人类免疫缺陷病毒(HIV)女性产后发病率的影响。
我们对1989年至1999年在单一参考中心分娩的401例感染HIV的女性进行了一项回顾性研究。将剖宫产的女性(n = 201),其中109例为择期剖宫产,92例为急诊剖宫产,与一组经阴道分娩的女性(n = 200)进行比较,该组由每次剖宫产之前感染HIV的女性组成。
12%的急诊剖宫产、6.4%的择期剖宫产以及4%的阴道分娩后发生了一种或多种严重并发症(P = 0.04)。在对产妇CD4淋巴细胞计数和产前出血进行校正的多变量分析中,与阴道分娩相比,择期剖宫产术后任何产后并发症(严重或轻微)的相对风险增加了1.85(范围为1.00 - 3.39),急诊剖宫产术后增加了4.17(范围为2.32 - 7.49)(P = 0.0001)。
感染HIV的女性产后发病率在急诊剖宫产而非择期剖宫产术后最高。