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Human mitochondrial NADP-dependent isocitrate dehydrogenase in man-mouse somatic cell hybrids.

作者信息

Bruns G A, Eisenman R E, Gerald P S

出版信息

Cytogenet Cell Genet. 1976;17(4):200-11. doi: 10.1159/000130713.

Abstract

Human mitochondrial NADP-dependent isocitrate dehydrogenase (IDH-2) is expressed in man-mouse somatic cell hybrids as a dimeric molecule. The gene specifing this enzyme was observed to be syntenic with the mannose phosphate isomerase locus in the 56 primary man-mouse clones in this series. The human IDH-2 locus, therefore, may be assigned to chromosome 15.

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