Scholl Dean, Adhya Sankar, Merril Carl R
Laboratory of Biochemical Genetics, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA.
J Bacteriol. 2002 May;184(10):2833-6. doi: 10.1128/JB.184.10.2833-2836.2002.
The lytic salmonella phage SP6 encodes a tail protein with a high degree of sequence similarity to the tail protein of the biologically unrelated lysogenic salmonella phage P22. The SP6 tail gene is flanked by an upstream region that contains a promoter and a downstream region that contains a putative Rho-independent transcription terminator, giving it a cassette or modular structure almost identical to the structure of the tail genes of coliphages K1E, K5, and K1-5. It now appears that SP6, K1-5, K5, and K1E are very closely related but have different tail fiber proteins, giving them different host specificities.
裂解性沙门氏菌噬菌体SP6编码一种尾部蛋白，该蛋白与生物学上不相关的溶原性沙门氏菌噬菌体P22的尾部蛋白具有高度的序列相似性。SP6尾部基因两侧分别是一个包含启动子的上游区域和一个包含推定的不依赖Rho转录终止子的下游区域，赋予其一种几乎与大肠杆菌噬菌体K1E、K5和K1-5的尾部基因结构相同的盒式或模块化结构。现在看来，SP6、K1-5、K5和K1E密切相关，但具有不同的尾丝蛋白，从而赋予它们不同的宿主特异性。
