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[与严重孕产妇发病相关的危险因素的决定因素:产前咨询期间的应用]

[Determinants of risk factors associated with severe maternal morbidity: application during antenatal consultations].

作者信息

Testa J, Ouédraogo C, Prual A, De Bernis L, Koné B

机构信息

DIM, CNHU, 01 BP 476, Cotonou, Bénin.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 2002 Feb;31(1):44-50.

PMID:11976577
Abstract

In order to assess the incidence of severe maternal mortality (SMM) and search for associated determinants of risk factors, a population-based survey of 20,326 pregnant women was conducted in six counties in West Africa (MOMA study). Complete files were available for 19,545 (96.2%) women. The rate of SMM, assessed with an overall indicator, was 6.7% (5.7-6.4). The relationship between SMM and various socio-economic features, gyneco-obstetrical antecedents and characteristics of the current pregnancy was studied. Multivariate analysis identified 10 factors of risk of SMM. Prevalence, adjusted odds-ratio, positive predictive value and adjusted attributable risk were determined for these ten factors. By decreasing order of positive predictive value, these factors were: hemorrhage during pregnancy (51.5%), antecedent cesarean (27.1%), high blood pressure (diastolic pressure 10 (18.9%), systolic pressure 14 (14.6%)), antecedent multiple pregnancy (15.8%), height 150 cm (12.9%), lack of fetal movements (12.6%), history of 3 stillborns (9.3%), age over 35 years (8%), nulliparity (7.3%), presence of disease during the pregnancy (7.1%). These results show the importance of antenatal consultation during which these factors are easily identifiable.

摘要

为了评估孕产妇严重死亡率(SMM)的发生率并寻找相关危险因素的决定因素,在西非六个县开展了一项基于人群的20326名孕妇的调查(MOMA研究)。19545名(96.2%)妇女有完整档案。用总体指标评估的SMM率为6.7%(5.7 - 6.4)。研究了SMM与各种社会经济特征、妇产科既往史及本次妊娠特征之间的关系。多变量分析确定了10个SMM危险因素。确定了这10个因素的患病率、调整后的比值比、阳性预测值和调整后的归因风险。按阳性预测值从高到低排序,这些因素依次为:孕期出血(51.5%)、既往剖宫产史(27.1%)、高血压(舒张压≥10 [18.9%],收缩压≥14 [14.6%])、既往多胎妊娠史(15.8%)、身高<150 cm(12.9%)、胎动减少(12.6%)、3次死产史(9.3%)、年龄>35岁(8%)、初产(7.3%)、孕期患病(7.1%)。这些结果表明了产前检查的重要性,在此期间这些因素易于识别。

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