Olech-Fudali E, Chibowski D, Skomra D, Walczyna B
Department of Pathomorphology, Medical University of Lublin.
Ann Univ Mariae Curie Sklodowska Med. 2001;56:319-25.
The aim of the study was the analysis of expression of estrogen (ER) and progesterone (PR) receptors in endometrial carcinomas. The expression of each of the receptors was examined with reference to such parameters as: patients' age, the relation to menopause, histological type and grading, the depth of myometrial infiltration and the presence of endometrial hyperplasia adjacent to the tumour. There were found very significant correlations between the degree of histological grading and expression of ER and PR and between values of index ER and PR. There was obtained correlation between the expression and endometrial hyperplasia only for PR.
本研究的目的是分析子宫内膜癌中雌激素（ER）和孕激素（PR）受体的表达情况。参照以下参数检查每种受体的表达：患者年龄、绝经关系、组织学类型和分级、肌层浸润深度以及肿瘤旁子宫内膜增生的存在情况。发现组织学分级程度与ER和PR的表达之间以及ER和PR指数值之间存在非常显著的相关性。仅PR的表达与子宫内膜增生之间存在相关性。
