de Graaf E J R, Doornebosch P G, Stassen L P S, Debets J M H, Tetteroo G W M, Hop W C J
Department of Surgery, IJsselland Hospital, Capelle aan den IJssel, The Netherlands.
Eur J Cancer. 2002 May;38(7):904-10. doi: 10.1016/s0959-8049(02)00050-3.
If curation is intended for rectal cancer, total mesorectal excision with autonomic nerve preservation (TME) is the gold standard. Transanal resection is tempting because of low mortality and morbidity rates. However, inferior tumour control, provoked by the limitations of the technique, resulted in its cautious application and use mainly for palliation. Transanal endoscopic microsurgery (TEM) is a minimal invasive technique for the local resection of rectal tumours. It is a one-port system, introduced transanally. An optical system with a 3D-view, 6-fold magnification and resolution as the human eye, together with the creation of a stabile pneumorectum, and specially designed instruments allow full-thickness excision under excellent view and a proper histological examination. The technique can also be applied for larger and more proximal tumours. Mortality, morbidity as well as incomplete excision rates are minimal. Local recurrence and survival rates seem comparable to TME in early rectal cancer. TEM is the method of choice when local resection of rectal cancer is indicated. Results justify a re-evaluation of the indications for the local excision of rectal cancer with a curative intent.
如果针对直肠癌进行根治性手术,保留自主神经的全直肠系膜切除术(TME)是金标准。经肛门切除术因死亡率和发病率低而颇具吸引力。然而,由于该技术的局限性导致肿瘤控制不佳,因此其应用较为谨慎,主要用于姑息治疗。经肛门内镜显微手术(TEM)是一种用于直肠肿瘤局部切除的微创技术。它是一种经肛门引入的单孔系统。具有三维视野、6倍放大率和与人眼分辨率相当的光学系统,加上建立稳定的直肠充气,以及专门设计的器械,可在良好视野下进行全层切除并进行适当的组织学检查。该技术也可应用于更大和更靠近近端的肿瘤。死亡率、发病率以及不完全切除率都很低。在早期直肠癌中,局部复发率和生存率似乎与TME相当。当需要对直肠癌进行局部切除时,TEM是首选方法。这些结果证明有必要重新评估具有治愈意图的直肠癌局部切除的适应症。