Nakamura Hiroshige, Morishita Ryuichi, Kaneda Yasufumi
Division of Gene Therapy Science, Graduate School of Medicine, Osaka University Medical School, Yamada-oka 2-2, Suita, Osaka 565-0871, Japan.
In Vivo. 2002 Jan-Feb;16(1):45-8.
The number of reports on in vivo gene therapies with decoy ODNs complexed with HVJ liposomes has recently increased. Diligent efforts to improve HVJ vectors as gene carriers and to expand the therapeutic applications of NFkB and E2F decoy ODNs will be important for the improved treatment of many genetic diseases.
近期，关于将诱饵寡核苷酸（ODN）与HVJ脂质体复合进行体内基因治疗的报道数量有所增加。为改进作为基因载体的HVJ载体并扩大NFkB和E2F诱饵ODN的治疗应用而做出的不懈努力，对于改善多种遗传疾病的治疗将具有重要意义。
