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用于人类内脏利什曼病诊断的凯特克斯

[Katex for the diagnosis of human visceral leishmaniasis].

作者信息

Hommel M, Sarkari B, Carney J, Chance M L

机构信息

Liverpool Scholl of Tropical Medicine, Pembrokeplace, Liverpool L3 5QA, UK.

出版信息

Med Trop (Mars). 2001;61(6):503-5.

Abstract

Katex is a latex agglutination test allowing highly specific detection Leishmania antigen in urine of patients with visceral leishmaniasis. A multicentric study of this new diagnostic tool which is also effective in patients co-infected by leishmaniasis and HIV is currently in progress in Sudan, India, Nepal, Brazil and Spain. The authors describe the utility of this technique in comparison with other routine diagnostic procedures such as microscopic examination and serological tests. Preliminary results suggest that it could be used to confirm infection in the field and to monitor treatment efficacy.

摘要

卡泰克斯是一种乳胶凝集试验,可高度特异性地检测内脏利什曼病患者尿液中的利什曼原虫抗原。目前,苏丹、印度、尼泊尔、巴西和西班牙正在对这种新的诊断工具进行多中心研究,该工具对同时感染利什曼病和艾滋病毒的患者也有效。作者描述了该技术与其他常规诊断程序(如显微镜检查和血清学检测)相比的实用性。初步结果表明,它可用于在现场确认感染情况并监测治疗效果。

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