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从一名慢性髓性白血病患者的脾脓肿中分离出肠炎沙门氏菌沃辛顿血清型。

Isolation of Salmonella enterica serotype Worthington from a splenic abscess in a patient with chronic myeloid leukemia.

作者信息

Ghadage D P, Bal A M

机构信息

B.J.Medical College Pune, India.

出版信息

Braz J Infect Dis. 2002 Apr;6(2):88-90. doi: 10.1590/s1413-86702002000200005. Epub 2003 Mar 25.

DOI:10.1590/s1413-86702002000200005
PMID:11980609
Abstract

Splenic abscesses are caused by Staphylococcus aureus, Streptococcus and bacteria belonging to the family Enterobacteriaceae. We report a case of splenic abscess caused by an unusual serotype of Salmonella. A 55 year old man was admitted with complaints of fever and abdominal pain. On the basis of clinical findings and laboratory reports, a diagnosis of chronic myeloid leukemia was made. Ultrasonography of the abdomen revealed a single large cystic lesion in the spleen. Percutaneous drainage of the abscess was carried out. Salmonella enterica serotype Worthington was isolated from a pus sample taken from the abscess. The isolate was resistant to ampicillin, gentamicin, cefotaxime, chloramphenicol and tetracycline, and sensitive to amikacin and norfloxacin. Serotype Worthington is an emerging pathogen. This is the first report of isolation of this serotype from a splenic abscess. In seriously ill patients, such infections should be treated with a combination of antibiotics to circumvent problems with multidrug resistance.

摘要

脾脓肿由金黄色葡萄球菌、链球菌和肠杆菌科细菌引起。我们报告一例由罕见血清型沙门氏菌引起的脾脓肿病例。一名55岁男性因发热和腹痛入院。根据临床检查结果和实验室报告,诊断为慢性粒细胞白血病。腹部超声检查发现脾脏有一个大的囊性病变。对脓肿进行了经皮引流。从脓肿采集的脓液样本中分离出肠炎沙门氏菌沃辛顿血清型。该分离株对氨苄西林、庆大霉素、头孢噻肟、氯霉素和四环素耐药,对阿米卡星和诺氟沙星敏感。沃辛顿血清型是一种新出现的病原体。这是首次从脾脓肿中分离出该血清型的报告。在重症患者中,此类感染应联合使用抗生素治疗,以避免多重耐药问题。

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