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谷氨酰胺的转运:乘坐N线然后换乘A线。

The glutamine commute: take the N line and transfer to the A.

作者信息

Chaudhry Farrukh A, Reimer Richard J, Edwards Robert H

机构信息

Graduate Program in Neuroscience, Department of Neurology, University of California at San Francisco School of Medicine, San Francisco, CA 94143, USA.

出版信息

J Cell Biol. 2002 Apr 29;157(3):349-55. doi: 10.1083/jcb.200201070.

Abstract

The transfer of glutamine between cells contributes to signaling as well as to metabolism. The recent identification and characterization of the system N and A family of transporters has begun to suggest mechanisms for the directional transfer of glutamine, and should provide ways to test its physiological significance in diverse processes from nitrogen to neurotransmitter release.

摘要

谷氨酰胺在细胞间的转运有助于信号传导和新陈代谢。最近对系统N和A家族转运体的鉴定与表征已开始揭示谷氨酰胺定向转运的机制,并应能提供方法来测试其在从氮代谢到神经递质释放等多种过程中的生理意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8602/2173294/119a536583cf/0201070f1.jpg

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