Botterel Francoise, Ichai P, Feray C, Bouree P, Saliba F, Tur Raspa R, Samuel D, Romand S
Service de Microbiologie, Departement de Parasitologie-Mycologie, Hopital de Bicetre, Faculté de Médecine Paris-Sud, 78 rue du Général Leclerc, 94275 Kremlin-Bicetre Cedex, France.
J Clin Microbiol. 2002 May;40(5):1648-50. doi: 10.1128/JCM.40.5.1648-1650.2002.
Disseminated toxoplasmosis is a life-threatening disease in liver transplant recipients that can result from an organ-transmitted infection. We report here a case of fatal disseminated toxoplasmosis after orthotopic liver transplantation from a seropositive donor (immunoglobulin G IgG and IgM(-)) in a patient who was nonimmune for toxoplasmosis prior to transplantation. Quantitative PCR analyses of various clinical specimens, including serum samples, appeared retrospectively to be a valuable diagnostic tool that might guide therapeutic attitudes.
播散性弓形虫病在肝移植受者中是一种危及生命的疾病，可由器官传播感染引起。我们在此报告一例原位肝移植后发生的致命性播散性弓形虫病病例，供者为血清学阳性（免疫球蛋白GIgG且IgM(-)），而受者在移植前对弓形虫病无免疫力。对包括血清样本在内的各种临床标本进行的定量PCR分析，回顾性来看似乎是一种有价值的诊断工具，可能会指导治疗策略。
