Ho I-Cheng, Glimcher Laurie H
Department of Immunology and Infectious Diseases, Harvard School of Public Health, 651 Huntington Avenue, FXB-2, Boston, MA 02115, USA.
Cell. 2002 Apr;109 Suppl:S109-20. doi: 10.1016/s0092-8674(02)00705-5.
The T helper lymphocyte is responsible for orchestrating an appropriate immune response to pathogens. To do so, it has evolved into two specialized subsets that direct type 1 and type 2 immunity. Here, we discuss the genetic programs that control lineage commitment of progenitor T helper cells along each of these pathways.
辅助性T淋巴细胞负责协调针对病原体的适当免疫反应。为此，它已分化为两个专门的亚群，分别主导1型和2型免疫。在此，我们讨论控制祖辅助性T细胞沿这些途径中每条途径的谱系定向的遗传程序。
