Shoji R, Murakami U, Shimizu T
Teratology. 1975 Dec;12(3):227-31. doi: 10.1002/tera.1420120303.
Effects of low-intensity ultrasonic irradiation on prenatal development of DHS and A/HeMk mice were studied. On day 8 of gestation (VP day = 0) pregnant females were exposed to ultrasonic waves with a frequency of 2.25 MHz and power of 40 mW/cm2 for 5 h. A low frequency of severe cranial and facial anomalies occurred that was attributable to the irradiation in both strains. The difference in frequency of malformed fetuses was marked between irradiated and untreated control A/HeMk mice, but not DHS mice. Fetal growth inhibition and death were also produced in both strains, although the possible effect of binding the pregnant mice for irradiation cannot be discounted.
研究了低强度超声辐照对DHS和A/HeMk小鼠产前发育的影响。在妊娠第8天（阴道栓日=0），对怀孕母鼠施加频率为2.25MHz、功率为40mW/cm2的超声波，持续5小时。两种品系中均出现了因辐照导致的严重颅脑和面部异常的低发生率。辐照的A/HeMk小鼠与未处理的对照小鼠之间畸形胎儿的频率差异明显，但DHS小鼠没有。两种品系中均出现了胎儿生长抑制和死亡情况，不过不能排除将怀孕小鼠束缚以进行辐照的可能影响。
