Nesarajah M S
Thorax. 1975 Oct;30(5):574-7. doi: 10.1136/thx.30.5.574.
Spirometric and lung volume measurements were carried out before and after treatment with diethylcarbamazine in 19 patients with tropical eosinophilia. The total lung capacity and vital capacity returned to or nearly to normal while the FEV1 and PEFR, though improved, tended to remain below normal, indicating some residual airways obstruction especially in patients whose treatment began more than one month from the onset of symptoms. The time taken for the pulmonary function to return to normal with treatment was found to be much longer than for the clinical and haematological response.
对19例热带嗜酸性粒细胞增多症患者在使用乙胺嗪治疗前后进行了肺量计和肺容量测量。总肺容量和肺活量恢复到或接近正常，而第一秒用力呼气容积（FEV1）和呼气峰值流速（PEFR）虽有所改善，但仍倾向于低于正常水平，这表明存在一些残留的气道阻塞，尤其是在症状出现后一个多月才开始治疗的患者中。发现肺功能恢复正常所需的时间比临床和血液学反应恢复正常的时间长得多。
