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颈椎侵袭性成骨细胞瘤伴完全神经功能恢复。

Destructive osteoblastoma of the cervical spine with complete neurologic recovery.

作者信息

Schneider M, Sabo D, Gerner H J, Bernd L

机构信息

Department of Orthopaedics, Orthopaedic University Hospital Heidelberg, Germany.

出版信息

Spinal Cord. 2002 May;40(5):248-52. doi: 10.1038/sj.sc.3101288.

DOI:10.1038/sj.sc.3101288
PMID:11987008
Abstract

STUDY DESIGN

Case report.

OBJECTIVE

To describe a patient with a large tumor lesion of the 6th vertebrae affecting surrounding soft tissue, and symptoms of cord compression. Histologic diagnosis indicated a destructive osteoblastoma following dorsal and anterior resection and internal fixation.

SETTING

University Hospital, Germany.

METHODS

A 23-year old male patient was admitted with a 2-month history of increasing upper extremity weakness and pain. X-ray and MRI indicated massive involvement of the anterior and posterior elements of the 6th vertebrae with a large soft tissue mass. Following emergency decompression and dorsal stabilization, the pathologic investigation revealed a destructive osteoblastoma. Subsequent dorsal and anterior resection with internal fixation were performed.

RESULTS

The patient initially presented with symptoms of beginning paraplegia of C6/7. According to the neurologic classification of spinal cord injury, motor function score was 56 and sensory function score 83. After emergency dorsal decompression and internal fixation with Luque-Instrumentation he showed increasing neurological recovery. Complete neurological recovery was achieved at 2 and 12-months postoperatively, following secondary dorsal and anterior resection of the tumor and internal fixation with bone cement (PalacosR) and Harms-cage. Radiologic signs of local recurrence were identified 1 year postoperatively.

CONCLUSION

Osteoblastoma of the cervical spine is rare. Patients often present with severe neurological symptoms due to significant tumor mass. Complete resection is necessary to regain full recovery, to prevent recurrence and, in some cases, malignant transformation.

摘要

研究设计

病例报告。

目的

描述一名患有第6节椎体巨大肿瘤病变并累及周围软组织及出现脊髓压迫症状的患者。组织学诊断显示在进行背侧和前路切除及内固定后为侵袭性成骨细胞瘤。

背景

德国大学医院。

方法

一名23岁男性患者因上肢无力和疼痛加重2个月入院。X线和磁共振成像显示第6节椎体的前后结构大量受累并伴有巨大软组织肿块。在进行紧急减压和背侧稳定术后,病理检查显示为侵袭性成骨细胞瘤。随后进行了背侧和前路切除及内固定。

结果

患者最初表现为C6/7节段开始出现截瘫症状。根据脊髓损伤的神经学分类,运动功能评分为56分,感觉功能评分为83分。在进行紧急背侧减压并用鲁克器械进行内固定后,他的神经功能逐渐恢复。在术后2个月和12个月,在对肿瘤进行二次背侧和前路切除并用骨水泥(帕拉科斯R)和哈姆斯椎间融合器进行内固定后,实现了完全神经功能恢复。术后1年发现局部复发的放射学迹象。

结论

颈椎成骨细胞瘤罕见。由于肿瘤肿块较大,患者常出现严重的神经症状。为实现完全康复、预防复发以及在某些情况下预防恶变,必须进行完整切除。

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