Peces R, Gil F, González F, Ablanedo P
Servicio de Nefrología Hospital Universitario La Paz Paseo de la Castellana, 261 28046 Madrid.
Nefrologia. 2002;22(1):79-82.
Skeletal brown tumours are relatively uncommon, and brown tumours that involve multiple bones are considered very rare. We describe a 29-year-old woman with chronic renal failure (CRF) who had undergone hemodialysis for 21 years and developed multiple brown tumours associated with severe secondary hyperparathyroidism. Computed tomography (CT) revealed multiple brown tumours involving scapula, ribs, spine and sacroiliac bone. Microscopic analysis of the brown tumour showed dense infiltration of the marrow space by reactive fibroblastic tissue with irregularly distributed multinucleated osteoclastic giants cells and marked increase in hematopoietic elements.
骨棕色瘤相对少见，而累及多骨的棕色瘤则极为罕见。我们报告一例29岁患有慢性肾衰竭（CRF）的女性，她已接受血液透析21年，并出现了与严重继发性甲状旁腺功能亢进相关的多发棕色瘤。计算机断层扫描（CT）显示棕色瘤累及肩胛骨、肋骨、脊柱和骶髂骨。棕色瘤的显微镜分析显示，反应性纤维组织密集浸润骨髓腔，伴有分布不均的多核破骨巨细胞，造血成分明显增加。
