Blinov V A
Vopr Onkol. 1975;21(4):23-8.
In rabbits transplanted Brown-Pearce carcinoma the content of nitrous compounds in tissues is changed in a different way: in the liver and kidneys -- nitrous compounds are accumulated, while in cardiac and skeletal muscles their concentration is diminished. It is found that tumor cells in mice with Ehrlich carcinoma accumulate radioactive aminoacid considerably faster than adjacent tissues not involved by neoplasma. A continuous glucose administration in tumor-bearing rabbits renders a marked nitrogen-saving effect by means of attenuation of catabolism of myoproteins, as a result of it the balance between the processes of synthesis and catabolism in host tissues is shifted toward synthesis.
在移植了布朗-皮尔斯癌的兔子中，组织中亚硝基化合物的含量变化各异：肝脏和肾脏中亚硝基化合物会蓄积，而心肌和骨骼肌中其浓度则降低。研究发现，患艾氏癌的小鼠肿瘤细胞积累放射性氨基酸的速度比未受肿瘤影响的相邻组织快得多。给患肿瘤的兔子持续输注葡萄糖，通过减弱肌蛋白的分解代谢产生显著的节省氮的效果，结果宿主组织中合成与分解代谢过程之间的平衡向合成方向转移。
