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[免疫疗法在支气管哮喘治疗中的意义]

[Significance of immunotherapy in treatment of bronchial asthma].

作者信息

Hałasa Józef, Hałasa Maciej

出版信息

Pol Merkur Lekarski. 2002 Feb;12(68):140-2.

PMID:11995252
Abstract

When first used, immunotherapy was applied to treatment of infectious diseases. Its high effectiveness gave an impulse to introduce this method in the treatment of allergic diseases, including bronchial asthma. In contrast to pharmacological treatment which treats only the symptoms in allergies, immunotherapy is presently considered to be the only causative treatment. Several conditions have to be fulfilled to obtain the effect of such treatment. Appropriate patients selection, use of the etiologically correct vaccine and continuing the treatment throughout several seasons are the conditions for the therapeutic success. In nonatopic intrinsic asthma or in atopic asthma complicated by bacterial infections the use of autologic or polyvalent (standard) bacterial vaccine should be considered. Because immunotherapy brings a risk of serious side effects such as anaphylactic reaction, only allergy specialist should be entitled to decide of the introduction of such treatment and to supervise its course.

摘要

免疫疗法首次应用于传染病的治疗。其高效性促使人们将该方法引入包括支气管哮喘在内的过敏性疾病的治疗中。与仅治疗过敏症状的药物治疗不同,免疫疗法目前被认为是唯一的病因治疗方法。要获得这种治疗效果,必须满足几个条件。选择合适的患者、使用病因正确的疫苗以及在几个季节中持续进行治疗是治疗成功的条件。在非特应性内源性哮喘或合并细菌感染的特应性哮喘中,应考虑使用自体或多价(标准)细菌疫苗。由于免疫疗法存在严重副作用的风险,如过敏反应,只有过敏专科医生才有资格决定是否采用这种治疗方法并监督其过程。

相似文献

1
[Significance of immunotherapy in treatment of bronchial asthma].[免疫疗法在支气管哮喘治疗中的意义]
Pol Merkur Lekarski. 2002 Feb;12(68):140-2.
2
Bacterial immunotherapy in bronchial asthma.
Allergol Immunopathol (Madr). 1979 Jan-Feb;7(1):47-54.
3
Bacterial immunotherapy of childhood bronchial asthma.儿童支气管哮喘的细菌免疫疗法。
Allergol Immunopathol (Madr). 1980 May-Jun;8(3):177-84.
4
How strong is the evidence that immunotherapy in children prevents the progression of allergy and asthma?免疫疗法对预防儿童过敏和哮喘进展的证据有多有力?
Curr Opin Allergy Clin Immunol. 2007 Dec;7(6):556-60. doi: 10.1097/ACI.0b013e3282f1d67e.
5
[Specific immunotherapy in allergic asthma].[过敏性哮喘的特异性免疫疗法]
Pneumologie. 2003 Feb;57(2):84-90. doi: 10.1055/s-2003-37151.
6
Prevention of allergic disease in childhood: clinical and epidemiological aspects of primary and secondary allergy prevention.儿童过敏性疾病的预防:一级和二级过敏预防的临床与流行病学方面
Pediatr Allergy Immunol. 2004 Jun;15 Suppl 16:4-5, 9-32. doi: 10.1111/j.1399-3038.2004.0148b.x.
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Immunotherapy: an option in the management of occupational asthma?
Curr Opin Allergy Clin Immunol. 2006 Apr;6(2):96-100. doi: 10.1097/01.all.0000216851.10571.64.
8
Safety and efficacy of allergen immunotherapy in the treatment of allergic rhinitis and asthma in real life.变应原免疫疗法在现实生活中治疗变应性鼻炎和哮喘的安全性与有效性。
Isr Med Assoc J. 2008 Dec;10(12):869-72.
9
Effect of specific immunotherapy added to pharmacologic treatment and allergen avoidance in asthmatic patients allergic to house dust mite.在对屋尘螨过敏的哮喘患者中,特异性免疫疗法联合药物治疗及避免接触变应原的效果。
J Allergy Clin Immunol. 2004 Apr;113(4):643-9. doi: 10.1016/j.jaci.2003.12.586.
10
[Bacterial infection in the etiology of bronchial asthma].[支气管哮喘病因中的细菌感染]
Patol Fiziol Eksp Ter. 1999 Jan-Mar(1):6-11.

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