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成人牙周炎治疗后牙齿松动度的统计建模

Statistical modeling of tooth mobility after treating adult periodontitis.

作者信息

Groselj Dusan, Grabec Igor

机构信息

Medical Faculty, Department of Dentistry, University of Ljubljana, Slovenia.

出版信息

Clin Oral Investig. 2002 Mar;6(1):28-38. doi: 10.1007/s00784-001-0147-y.

Abstract

The healing process following periodontal surgery for advanced adult periodontitis is described. Of the various indicators, tooth mobility (TM) is considered, and its relation to surgical treatment and the time lapse from the flap surgery is quantitatively modeled by non-parametric regression. Mobility is measured by an electronic apparatus, which also automatically performs the modeling. A new statistical method for TM prediction is demonstrated, and its quality is estimated. We show that the quality at the first step of prediction is approximately 0.7. This indicates that the prediction method is able to model the effect of surgery on the healing process, although the random scattering of TM data recorded in the examined group is relatively large. The influence of periodontal surgery on TM, alone and in combination with systemic metronidazole, is quantitatively characterized in two groups of 12 patients each. In the test group, which received metronidazole, TM decreased significantly 1 week postoperatively, compared to the control group without the antibiotic. The gingival fluid flow rate (GFFR) and the percentage of spirochete morphotypes detected by darkfield microscopy exhibited a similar dependence. Significant differences in TM, GFFR and the percentage of spirochetes between the two groups were observed over a period of several weeks. Probing depths (PD) in both groups at 2 and 12 months after surgery did not reveal any category with pockets deeper than 4 mm. A gain of clinical attachment level of more than 2 mm (CAL) was observed at measurements of 16.7% and 10.6% on the test and control groups, respectively, 1 year after surgery.

摘要

描述了晚期成人牙周炎牙周手术后的愈合过程。在各种指标中,考虑了牙齿松动度(TM),并通过非参数回归对其与手术治疗以及翻瓣手术后时间间隔的关系进行了定量建模。牙齿松动度通过电子设备测量,该设备还能自动进行建模。展示了一种用于预测TM的新统计方法,并对其质量进行了评估。我们表明,预测第一步的质量约为0.7。这表明该预测方法能够模拟手术对愈合过程的影响,尽管在被检查组中记录的TM数据随机散点相对较大。在每组12名患者的两组中,定量表征了牙周手术单独以及与全身使用甲硝唑联合使用对TM的影响。在接受甲硝唑的试验组中,与未使用抗生素的对照组相比,术后1周TM显著下降。牙龈液流速(GFFR)和暗视野显微镜检测到的螺旋体形态类型百分比表现出类似的依赖性。在几周的时间里,观察到两组之间在TM、GFFR和螺旋体百分比方面存在显著差异。手术后2个月和12个月时,两组的探诊深度(PD)均未发现有袋深超过4mm的情况。术后1年,试验组和对照组分别有16.7%和10.6%的测量值显示临床附着水平增加超过2mm(CAL)。

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