Citko A, Mnich Z, Rajkowska-Franke E, Rogowski F, Trembaczowski E, Kostrzewska A
Acta Physiol Pol. 1975 Jul-Aug;26(4):419-28.
The aim of this work was to examine the effect of a hypertonic solution (Krebs solution + 290 mM urea) on K+ and Na+ transport. The experiments were carried out on the guinea-pig taenia coli preparations using the method of Na-24 and K-24 loading and washout. The efflux curves were analysed by means of the digital computer technique. The following parameters were determined: efflux rate constant k2, influx rate constant k1, intracellular ion concentration C1 ion flux M and permeability P. Any significant difference between PNa/PK ratio in hypertonic urea and isotonic Krebs solutions was found.
这项工作的目的是研究高渗溶液（ Krebs 溶液 + 290 mM 尿素）对钾离子和钠离子转运的影响。实验采用钠 - 24 和钾 - 24 加载及洗脱方法，在豚鼠结肠带制备物上进行。通过数字计算机技术分析流出曲线。测定了以下参数：流出速率常数 k2、流入速率常数 k1、细胞内离子浓度 C1、离子通量 M 和渗透率 P。未发现高渗尿素溶液和等渗 Krebs 溶液中 PNa/PK 比值有任何显著差异。
