Chibwana C, Mhango T, Molyneux E M
Department of Paediatrics, Queen Elizabeth Central Hospital, College of Medicine, Chichiri, Blantyre, Malawi.
East Afr Med J. 2001 Jun;78(6):292-5. doi: 10.4314/eamj.v78i6.9021.
To record the number of children with poisoning admitted to the Queen Elizabeth Central Hospital over one year; to note the causes, clinical and laboratory findings and outcome of each poisoning event and; to highlight any preventable pattern in such events.
A one year prospective study was undertaken of all children admitted to the Queen Elizabeth Central Hospital with a history or clinical evidence of acute poisoning. Socio-demographic, clinical and laboratory data were recorded and outcome noted for each child on specially prepared forms. Data were entered and then analysed in Epi-Info 6.
Department of Paediatrics, Queen Elizabeth Central Hospital, Blantyre, Malawi.
Children were treated forpoisoning according to national guidelines; supportive care and active antidote were given as necessary.
Length of stay in hospital and mortality were primary outcome measures.
One hundred and forty four cases were admitted, 118 (82%) were accidental, in 19 cases the reason was unknown and six (4.2%) were non accidental. Carbonate poisoning caused 32% (n=46) of admissions and paraffin 16.7% (n=24). The age range of poisoned children was three weeks to 14 years with a mean of four years and eight months. Eleven deaths occurred, six of which were due to traditional medicine intoxication.
Most poisoning were preventable and the public needs to be made aware of the dangers of household agents, advised how to store them in the home and what to do if a child ingests a poisonous substance. Traditional medicines are particularly dangerous to give to infants less than one year old and carry a high mortality.
记录一年间入住伊丽莎白女王中央医院的中毒儿童数量;记录每次中毒事件的原因、临床及实验室检查结果和转归;并突出此类事件中任何可预防的模式。
对所有因急性中毒病史或临床证据入住伊丽莎白女王中央医院的儿童进行为期一年的前瞻性研究。使用特制表格记录每个儿童的社会人口学、临床和实验室数据,并记录转归。数据录入Epi-Info 6后进行分析。
马拉维布兰太尔伊丽莎白女王中央医院儿科。
根据国家指南对中毒儿童进行治疗;必要时给予支持治疗和特效解毒剂。
住院时间和死亡率为主要观察指标。
共收治144例,118例(82%)为意外中毒,19例原因不明,6例(4.2%)为非意外中毒。碳酸盐中毒导致32%(n = 46)的入院病例,石蜡中毒导致16.7%(n = 24)。中毒儿童年龄范围为3周至14岁,平均年龄为4岁8个月。11例死亡,其中6例死于传统药物中毒。
大多数中毒事件是可预防的,需要让公众了解家用制剂的危险性,告知如何在家中储存这些制剂以及儿童摄入有毒物质时应如何处理。传统药物对1岁以下婴儿尤其危险,死亡率很高。