Wnuk A, Rytwinski K, Rychlowska M, Klepacka T, Michalak E
Samodzielna Pracownia Cytometrii, Instytut Matki i Dziecka, Kasprzaka 17a, 01-211 Warszawa, Poland.
Med Wieku Rozwoj. 2001 Jul-Sep;5(3):283-90.
Flow cytometry analysis has been used to measure the S phase in paraffin embedded osteosarcoma tissues of 22 children and adolescents who were surgically treated. The aim of this study was the assessment of S phase cell cycle in relation to survival, localization of tumour and histopathological grading. Our findings demonstrate the usefulness of flow cytometry determination of S phase cell cycle as a prognostic factor. Higher percentage of S phase cells predict worse prognosis.
