Reller L B, Maddoux G L, Eckman M R, Pappas G
Ann Intern Med. 1975 Nov;83(5):664-6. doi: 10.7326/0003-4819-83-5-664.
Oerskovia turbata is a yellow, motile actinomycete, which before now has only been found in soil and has not been known to cause disease in man or animals. It was isolated from 29 cultures of blood taken during 6 months from an urban pensioner after homograft replacement of his aortic valve. The combination of ampicillin, sulfamethoxazole, and trimethoprim was lethal for O. turbata in vitro; however, antimicrobial therapy alone failed to eradicate the patient's infection. Cure was achieved after the infected homograft was replaced with a prosthetic aortic valve. Although the source of O. turbata in this patient is unknown, sterilization of homograft valves with antimicrobial solutions is difficult. Moreover, environmental contamination during cardiopulmonary bypass is common. Oerskovia turbata is another opportunistic pathogen of man.
浑浊奥尔森氏菌是一种黄色、可运动的放线菌，此前仅在土壤中发现，尚无在人类或动物中致病的报道。从一名城市退休老人主动脉瓣同种异体移植术后6个月内采集的29份血培养物中分离出了该菌。氨苄西林、磺胺甲恶唑和甲氧苄啶联合用药在体外对浑浊奥尔森氏菌具有致死性；然而，仅用抗菌治疗未能根除该患者的感染。在用人工主动脉瓣替换感染的同种异体移植瓣膜后实现了治愈。虽然该患者体内浑浊奥尔森氏菌的来源不明，但用抗菌溶液对同种异体移植瓣膜进行消毒很困难。此外，体外循环期间的环境污染很常见。浑浊奥尔森氏菌是人类的另一种机会致病菌。
