362个未刺激周期中单卵母细胞胞浆内单精子注射的结果。
Results of intracytoplasmic sperm injection of single oocyte in 362 unstimulated cycles.
作者信息
Vlaisavljević Veljko, Kovacic Borut, Reljic Milan, Lovrec Vida Gavrić, Sajko Mojca Cizek
机构信息
Department of Reproductive Medicine and Gynecologic Endocrinology, Maribor Teaching Hospital, Slovenia.
出版信息
J Assist Reprod Genet. 2002 Mar;19(3):127-31. doi: 10.1023/a:1014784721056.
PURPOSE
The purpose was to test the adequacy of unstimulated cycles for intracytoplasmic sperm injection (ICSI) and to evaluate implantation and pregnancy rates in three different age groups.
METHODS
ICSI was performed in 362 unstimulated cycles in women up to 45 years old. All cycles were monitored by serum estradiol, urinary LH, and ultrasound.
RESULTS
The delivery rate per started cycle was higher in patients younger than 36 (9.4%) than in cycles with patient's age between 36 and 39 years (4.8%) or older than 40 (4.6%) but the difference was not statistically significant. In all groups, the fertilization rate was similar (70.4, 77.6, and 84.8%, respectively). The pregnancy rate per cycle and the pregnancy rate per puncture was similar in the group of patients in age between 36 and 39 years (8.3 and 9.7%) and those older than 40 (7.7 and 9.3%).
CONCLUSIONS
Unstimulated cycles monitored by serum estradiol, urinary LH, and ultrasound can produce an acceptable pregnancy rate after ICSI procedure only in patients younger than 36.
目的
本研究旨在测试未刺激周期用于卵胞浆内单精子注射（ICSI）的可行性，并评估三个不同年龄组的着床率和妊娠率。
方法
对362例45岁及以下女性进行了未刺激周期的ICSI。所有周期均通过血清雌二醇、尿促黄体生成素（LH）和超声进行监测。
结果
起始周期的分娩率在年龄小于36岁的患者中（9.4%）高于年龄在36至39岁之间的周期（4.8%）或大于40岁的周期（4.6%），但差异无统计学意义。在所有组中，受精率相似（分别为70.4%、77.6%和84.8%）。年龄在36至39岁之间的患者组（8.3%和9.7%）与年龄大于40岁的患者组（7.7%和9.3%）的每个周期妊娠率和每次穿刺妊娠率相似。
结论
仅在年龄小于36岁的患者中，通过血清雌二醇、尿LH和超声监测的未刺激周期在ICSI术后可产生可接受的妊娠率。
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