Franco Ramon A, Singh Bhuvanesh, Har-El Gady
Department of Otology and Laryngology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston 02114, USA.
J Voice. 2002 Mar;16(1):92-5. doi: 10.1016/s0892-1997(02)00077-2.
Cartilaginous tumors of the larynx represent less than 1% of laryngeal tumors. Chondroma and "low-grade" chondrosarcoma are the most common; 70%-75% of these tumors arise on the endolaryngeal surface of the posterior lamina of the cricoid cartilage. The clinical presentation is varied and directly dependent on the size and location of the tumor; stridor, hoarseness, dyspnea, or a neck mass are common presenting signs. CT scanning in the axial plane is the mainstay of radiographic imaging due to its ability to show size, extent of the tumor, and invasion into surrounding structures. Surgical extirpation is the standard therapy with no role for radiation therapy or chemotherapy. Although significant recurrence rates have been reported, there is not a significant difference between initial conservative therapy followed by salvage therapy versus initial radical therapy.
喉软骨肿瘤占喉肿瘤的比例不到1%。软骨瘤和“低级别”软骨肉瘤最为常见；这些肿瘤的70%-75%发生在环状软骨后板的喉内表面。临床表现多样，直接取决于肿瘤的大小和位置；喘鸣、声音嘶哑、呼吸困难或颈部肿块是常见的症状。由于轴向CT扫描能够显示肿瘤的大小、范围以及对周围结构的侵犯情况，因此它是影像学检查的主要手段。手术切除是标准治疗方法，放疗或化疗不起作用。尽管有报道称复发率较高，但初始保守治疗后行挽救性治疗与初始根治性治疗之间并无显著差异。
