Levy Joseph
Children's Digestive Health Center, Children's Hospital of New York Presbyterian, 3959 Broadway, BHN-726, New York, NY 10032-3784, USA.
Curr Gastroenterol Rep. 2002 Jun;4(3):259-65. doi: 10.1007/s11894-002-0072-5.
Electrogastrography (EGG), the measurement of gastric pacemeaker activity by means of surface electrodes, provides a noninvasive technique to detect and quantify the characteristics of the gastric slow wave. With a predominant frequency of three cycles per minute, the activity of the specialized cells responsible for this pacing, the interstitial cells of Cajal, is crucial in providing the underlying electrophysiologic changes that enable coordinated smooth muscle contraction and synchronized peristalsis. Advances in electronics and software to define frequency distribution, stability of the signal, postprandial changes, and other parameters have contributed to more widespread interest in EGG and its application to the investigation of functional gastrointestinal disturbances. Definition of pediatric norms and postnatal changes in the EGG of premature infants has provided the foundation for further studies investigating correlative changes with such important functions as gastric emptying and motility. The EGG remains a promising diagnostic tool. Future studies will help define its usefulness in identifying abnormal functions of the interstitial cells of Cajal.
胃电图(EGG)通过表面电极测量胃起搏器活动,提供了一种检测和量化胃慢波特征的非侵入性技术。负责这种起搏的特殊细胞即 Cajal 间质细胞,其活动以每分钟三个周期的频率为主,对于提供使平滑肌协调收缩和同步蠕动的潜在电生理变化至关重要。在定义频率分布、信号稳定性、餐后变化及其他参数方面,电子学和软件的进展促使人们对 EGG 及其在功能性胃肠紊乱研究中的应用产生了更广泛的兴趣。早产儿 EGG 的儿科规范及出生后变化的定义,为进一步研究胃排空和蠕动等重要功能的相关变化奠定了基础。EGG 仍然是一种有前景的诊断工具。未来的研究将有助于确定其在识别 Cajal 间质细胞异常功能方面的效用。