Polkey Michael I
Royal Brompton Hospital, Fulham Road, London SW3 6NP, UK.
Chest. 2002 May;121(5 Suppl):131S-135S. doi: 10.1378/chest.121.5_suppl.131s.
This article explores the hypothesis that dyspnea in patients with COPD arises from an imbalance between the load placed on the respiratory muscle pump and its capacity. Evidence to support this concept is presented, and possible therapeutic approaches are discussed.