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To whom do the research findings apply?

作者信息

Furberg Curt D

机构信息

Department of Public Health Sciences, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1063, USA.

出版信息

Heart. 2002 Jun;87(6):570-4. doi: 10.1136/heart.87.6.570.

DOI:10.1136/heart.87.6.570
PMID:12010948
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1767149/
Abstract
摘要

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To whom do the research findings apply?这些研究结果适用于谁?
Heart. 2002 Jun;87(6):570-4. doi: 10.1136/heart.87.6.570.
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Philosophy on trial: examining ethics of clinical investigations.受审的哲学:审视临床研究的伦理问题
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Paternalism no problem.家长作风没问题。
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本文引用的文献

1
Clinical Implications of Recent Findings from the Antihypertensive and Lipid-Lowering Treatment To Prevent Heart Attack Trial (ALLHAT) and Other Studies of Hypertension.降压和降脂治疗预防心脏病发作试验(ALLHAT)及其他高血压研究近期结果的临床意义
Ann Intern Med. 2001 Dec 18;135(12):1074-8. doi: 10.7326/0003-4819-135-12-200112180-00011.
2
Relation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: a randomized controlled trial.吉非贝齐治疗及血脂水平与主要冠状动脉事件的关系:退伍军人事务部高密度脂蛋白胆固醇干预试验(VA-HIT):一项随机对照试验。
JAMA. 2001 Mar 28;285(12):1585-91. doi: 10.1001/jama.285.12.1585.
3
Underrepresentation of patients 65 years of age or older in cancer-treatment trials.65岁及以上患者在癌症治疗试验中的代表性不足。
N Engl J Med. 1999 Dec 30;341(27):2061-7. doi: 10.1056/NEJM199912303412706.
4
Incommunicable knowledge? Interpreting and applying the results of clinical trials and meta-analyses.不可言传的知识?解读与应用临床试验及荟萃分析的结果。
J Clin Epidemiol. 1998 Apr;51(4):289-95. doi: 10.1016/s0895-4356(97)00293-x.
5
Valvular heart disease associated with fenfluramine-phentermine.与芬氟拉明-苯丙胺相关的心脏瓣膜病。
N Engl J Med. 1997 Aug 28;337(9):581-8. doi: 10.1056/NEJM199708283370901.
6
Underrepresentation of women in clinical drug trials.女性在临床药物试验中的代表性不足。
Clin Pharmacol Ther. 1993 Jul;54(1):11-5. doi: 10.1038/clpt.1993.102.
7
Influence of adherence to treatment and response of cholesterol on mortality in the coronary drug project.冠状动脉药物项目中治疗依从性和胆固醇反应对死亡率的影响。
N Engl J Med. 1980 Oct 30;303(18):1038-41. doi: 10.1056/NEJM198010303031804.
8
Coronary artery surgery study (CASS): a randomized trial of coronary artery bypass surgery. Comparability of entry characteristics and survival in randomized patients and nonrandomized patients meeting randomization criteria.
J Am Coll Cardiol. 1984 Jan;3(1):114-28.
9
Mortality in non-consenters in a post-myocardial infarction trial.心肌梗死后试验中未同意参与者的死亡率。
J Intern Med. 1990 Sep;228(3):253-6. doi: 10.1111/j.1365-2796.1990.tb00227.x.
10
The n-of-1 randomized controlled trial: clinical usefulness. Our three-year experience.
Ann Intern Med. 1990 Feb 15;112(4):293-9. doi: 10.7326/0003-4819-112-4-293.