Black F Owen
Legacy Clinical Research and Technology Center, Department of Neurotology Research, Portland, OR 97208-3950, USA.
Am J Obstet Gynecol. 2002 May;186(5 Suppl Understanding):S204-9. doi: 10.1067/mob.2002.122602.
Nausea and vomiting of pregnancy shares many characteristics with motion sickness, a vestibular dependent phenomenon. A number of physiologic changes that occur in normal pregnancy are also known to accompany nausea and vomiting in patients with motion sickness and certain vestibular disorders. This chapter summarizes some shared features of both phenomena. The unmasking of subclinical vestibular disorders may account for some cases of hyperemesis gravidarum. Hormonal effects on neurotransmitter function may also play a role in nausea and vomiting of pregnancy and in some vestibular disorders; however, the specific neural mechanisms of nausea and vomiting have not been identified. Until the neurochemical processes underlying these phenomena are understood, prevention and management will remain in the domain of astute, but so far limited, clinical observation.
妊娠恶心和呕吐与晕动病有许多共同特征，晕动病是一种依赖前庭的现象。正常妊娠期间发生的一些生理变化也见于晕动病患者和某些前庭疾病患者的恶心和呕吐。本章总结了这两种现象的一些共同特征。亚临床前庭疾病的暴露可能是某些妊娠剧吐病例的原因。激素对神经递质功能的影响也可能在妊娠恶心和呕吐以及某些前庭疾病中起作用；然而，恶心和呕吐的具体神经机制尚未明确。在了解这些现象背后的神经化学过程之前，预防和管理仍将依赖敏锐但目前有限的临床观察。
