Biran G, Golan A, Sagiv R, Glezerman M, Menczer J
Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Holon, Israel.
Eur J Gynaecol Oncol. 2002;23(2):157-60.
The purpose of the present report was to assess the conversion rate from laparoscopy to laparotomy due to adnexal malignancy and to identify factors that might assist in the selection of the appropriate operative approach in patients with suspicious adnexal masses.
A retrospective review of the medical records of women who underwent laparoscopy due to ultrasonically complex adnexal masses. Ninety-five consecutive patients fulfilling these criteria, were identified. A comparison of patients with benign tumors who had laparoscopy only to those with invasive malignancies in whom laparoscopy was converted to laparotomy was performed.
Malignancy was diagnosed in 18 (18.9%) patients. In 13 patients with malignancy (two borderline and 11 invasive), comprising 72.2% of the malignancies and 13.7% of the total group with complex adnexal masses, the laparoscopy was converted to laparotomy. Age of more than 50 years and a serum CA125 level above 35 U/ml were significantly more common in the malignant than in the benign group (90.9% vs. 15.6% and 63.6% vs. 11.6%, respectively; p < 0.0001 and p < 0.003, respectively). When both factors were present, the sensitivity and specificity for malignancy were 73.3% and 93.2%, respectively, and the positive and negative predictive values 73.3% and 95.6%, respectively.
When an ultrasonically complex adnexal mass is encountered, predictive factors for malignancy should be taken into account before the mode of intervention is chosen. The conversion from laparoscopy to laparotomy because of an invasive malignant tumor is acceptable, if it is performed immediately and a gynecologic oncologist is on stand-by.
本报告旨在评估因附件恶性肿瘤导致的腹腔镜手术转为开腹手术的转化率,并确定有助于选择可疑附件包块患者合适手术方式的因素。
回顾性分析因超声检查发现附件包块而接受腹腔镜手术的女性患者的病历。确定了连续95例符合这些标准的患者。对仅接受腹腔镜手术的良性肿瘤患者与腹腔镜手术转为开腹手术的浸润性恶性肿瘤患者进行了比较。
18例(18.9%)患者被诊断为恶性肿瘤。13例恶性肿瘤患者(2例交界性和11例浸润性),占恶性肿瘤患者的72.2%,占附件包块复杂患者总数的13.7%,腹腔镜手术转为开腹手术。恶性肿瘤组患者年龄超过50岁和血清CA125水平高于35 U/ml的情况明显比良性肿瘤组更常见(分别为90.9%对15.6%和63.6%对11.6%;p分别<0.0001和p<0.003)。当两个因素都存在时,恶性肿瘤的敏感性和特异性分别为73.3%和93.2%,阳性和阴性预测值分别为73.3%和95.6%。
当遇到超声检查发现的附件复杂包块时,在选择干预方式之前应考虑恶性肿瘤的预测因素。如果因浸润性恶性肿瘤立即进行腹腔镜手术转为开腹手术且有妇科肿瘤学家待命,这种转换是可以接受