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Mechanisms of bone loss and gain in untreated and treated osteoporosis.

作者信息

Compston Juliet

机构信息

Department of Medicine, University of Cambridge School of Clinical Medicine, UK.

出版信息

Endocrine. 2002 Feb;17(1):21-7. doi: 10.1385/ENDO:17:1:21.

DOI:10.1385/ENDO:17:1:21
PMID:12014699
Abstract
摘要

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3
Effects of different regimens of sodium fluoride treatment for osteoporosis on the structure, remodeling and mineralization of bone.不同氟化钠治疗方案对骨质疏松症患者骨骼结构、重塑及矿化的影响
Osteoporos Int. 1998;8(5):428-35. doi: 10.1007/s001980050087.
4
Prolonged treatments with antiresorptive agents and PTH have different effects on bone strength and the degree of mineralization in old estrogen-deficient osteoporotic rats.在老年雌激素缺乏的骨质疏松大鼠中，使用抗吸收剂和甲状旁腺激素进行长期治疗对骨强度和矿化程度有不同影响。
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Effect of sodium fluoride, calcium, phosphate, and vitamin D2 on trabecular bone balance and remodeling in osteoporotics.氟化钠、钙、磷和维生素D2对骨质疏松症患者小梁骨平衡及重塑的影响。
Bone. 1985;6(5):381-9. doi: 10.1016/8756-3282(85)90337-0.
6
[Diagnostic imaging of treatment in osteoporosis: PTH].骨质疏松症治疗的诊断成像：甲状旁腺激素
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The therapeutic use of bisphosphonates.双膦酸盐的治疗用途。
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New treatments for osteoporosis.骨质疏松症的新疗法。
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Treatment of osteoporosis with sodium fluoride or parathyroid hormone.用氟化钠或甲状旁腺激素治疗骨质疏松症。
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Small bone-building fragments of parathyroid hormone: new therapeutic agents for osteoporosis.甲状旁腺激素的小骨生成片段：骨质疏松症的新型治疗药物。
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Aging alters bone-fat reciprocity by shifting in vivo mesenchymal precursor cell fate towards an adipogenic lineage.衰老通过使体内间充质前体细胞命运向脂肪生成谱系转变来改变骨-脂肪相互关系。
Bone. 2016 Apr;85:29-36. doi: 10.1016/j.bone.2016.01.014. Epub 2016 Jan 19.
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The effects of binge alcohol exposure on bone resorption and biomechanical and structural properties are offset by concurrent bisphosphonate treatment.同时进行双膦酸盐治疗可抵消暴饮酒精对骨吸收以及生物力学和结构特性的影响。
Alcohol Clin Exp Res. 2004 Jan;28(1):182-91. doi: 10.1097/01.ALC.0000108661.41560.BF.

本文引用的文献

1
Anabolic actions of PTH in the skeletons of animals.
J Musculoskelet Neuronal Interact. 2001 Sep;2(1):33-47.
2
Continuous parathyroid hormone and estrogen administration increases vertebral cancellous bone volume and cortical width in the estrogen-deficient rat.持续给予甲状旁腺激素和雌激素可增加雌激素缺乏大鼠的椎骨松质骨体积和皮质宽度。
J Bone Miner Res. 2001 Jul;16(7):1300-7. doi: 10.1359/jbmr.2001.16.7.1300.
3
Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis.甲状旁腺激素（1-34）对绝经后骨质疏松症女性骨折及骨密度的影响。
N Engl J Med. 2001 May 10;344(19):1434-41. doi: 10.1056/NEJM200105103441904.
4
Effects of suppressed bone turnover by bisphosphonates on microdamage accumulation and biomechanical properties in clinically relevant skeletal sites in beagles.双膦酸盐抑制骨转换对比格犬临床相关骨骼部位微损伤积累和生物力学性能的影响。
Bone. 2001 May;28(5):524-31. doi: 10.1016/s8756-3282(01)00414-8.
5
Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic women.阿仑膦酸盐通过增加骨质疏松症女性骨组织的平均矿化程度来增强骨骼强度。
Bone. 2000 Nov;27(5):687-94. doi: 10.1016/s8756-3282(00)00376-8.
6
Histomorphometric evidence for increased bone turnover without change in cortical thickness or porosity after 2 years of cyclical hPTH(1-34) therapy in women with severe osteoporosis.在患有严重骨质疏松症的女性中，经两年周期性人甲状旁腺激素（1-34）[hPTH(1-34)]治疗后，骨转换增加但皮质厚度或骨孔隙率无变化的组织形态计量学证据。
Bone. 2000 Aug;27(2):311-8. doi: 10.1016/s8756-3282(00)00316-1.
7
A comparison of the effects of raloxifene and estrogen on bone in postmenopausal women.雷洛昔芬与雌激素对绝经后女性骨骼影响的比较。
J Clin Endocrinol Metab. 2000 Jun;85(6):2197-202. doi: 10.1210/jcem.85.6.6654.
8
Effects of alendronate on bone quality and remodeling in glucocorticoid-induced osteoporosis: a histomorphometric analysis of transiliac biopsies.阿仑膦酸盐对糖皮质激素诱导的骨质疏松症骨质量和重塑的影响：经髂骨活检的组织形态计量学分析
J Bone Miner Res. 2000 Apr;15(4):754-62. doi: 10.1359/jbmr.2000.15.4.754.
9
True strength.
J Bone Miner Res. 2000 Apr;15(4):621-5. doi: 10.1359/jbmr.2000.15.4.621.
10
Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib.双膦酸盐抑制骨转换会增加微损伤积累，并降低犬肋骨的一些生物力学特性。
J Bone Miner Res. 2000 Apr;15(4):613-20. doi: 10.1359/jbmr.2000.15.4.613.