Sivalingam N, Surinder S
Department of Obstetrics & Gynaecology, General Hospital Ipoh, Perak.
Med J Malaysia. 2001 Dec;56(4):451-9.
Intra-umbilical injection of oxytocin has been used to hasten placental separation in retained placenta. A randomised controlled trial was done on 35 consequent women who fulfilled the criteria for retained placenta at the Department of Obstetrics & Gynaecology Ipoh Hospital. Nineteen patients who were recruited into the study group received intraumbilical injection of 301U oxytocin in 27mls saline. Another 16 patients who were in the control group received 30mls of 0.9% sodium chloride (placebo). The primary outcome measured was the need for manual removal of placenta (MRP). Nine out of the 19 patients in the oxytocin group required MRP while 10/16 in the control group required MRP. There was a 24% reduction (95% C.I. 0.41 to 1.39) in the need for MRP in the study group compared to the saline group. our results indicate that intra-umbilical vein injection of oxytocin is not clinically useful for the removal of a retained placenta.
脐内注射催产素已被用于加速胎盘滞留时胎盘的娩出。在怡保医院妇产科对35例符合胎盘滞留标准的连续产妇进行了一项随机对照试验。纳入研究组的19例患者在27毫升生理盐水中接受了30国际单位催产素的脐内注射。对照组的另外16例患者接受了30毫升0.9%氯化钠（安慰剂）。所测量的主要结局是是否需要人工剥离胎盘（MRP）。催产素组的19例患者中有9例需要人工剥离胎盘，而对照组的16例中有10例需要人工剥离胎盘。与生理盐水组相比，研究组人工剥离胎盘的需求降低了24%（95%置信区间0.41至1.39）。我们的结果表明，脐内静脉注射催产素在临床上对去除滞留胎盘并无用处。
