Wang Wenjuan, Wang Kean, Li Tianlin, Xiang Hongding, Ma Linmao, Fu Zhenying, Chen Junshi, Liu Zunyong, Bai Jin, Feng Jinguan, Jin Shuxiang, Li Yanqin, Qin Ruli, Chen Hong
Chinese Academy of Preventive Medicine, Beijing 100050, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2002 Feb;23(1):16-9.
Discussion on utility and purposed value of obesity and abdomen obesity when body mass index (BMI), waist circumference (WC), waist to hip ratio (WHR) used as indexes predicting hypertension, hyper-blood glucose, and both clusters, to provide scientific basis for the decision on the indexes and their cut-off points of obesity and abdomen obesity in Chinese people.
Using the data of diabetes mellitus (DM) from epidemiological studies carried out in 11 provinces/autonomous regions/municipalities of China from July 1995 to June 1997. Partial relative analysis, logistic multi-factors regression analysis, interaction analysis were used. Relative risk (RR), attributable risk proportion (ARP) and population attributable risk proportion (PARP) of hypertension, hyper-blood glucose, and the both cluster as BMI, WC, WHR with the different cut off points were analysed.
Since the maleficent extent of exposure factors to diseases, the acceptability for overweight and obesity in population, and the prevention and care for overweight and obesity were just in the introduction stage in China. The utility value of predicted hypertension, hyper-blood glucose in BMI and WC seemed to be better then in WHR. We suggested that BMI used as the obesity index, with the diagnostic cut-off point BMI >/= 24. WC as the abdomen obesity index. The diagnostic cut-off points are suggested to be WC >/= 85 cm in males, and WC >/= 80 cm in females.
探讨体质指数(BMI)、腰围(WC)、腰臀比(WHR)作为预测高血压、高血糖及两者聚集性的指标时,肥胖及腹型肥胖的应用价值和目标值,为我国人群肥胖及腹型肥胖指标及其切点的决策提供科学依据。
采用1995年7月至1997年6月在中国11个省/自治区/直辖市进行的糖尿病流行病学研究资料。运用偏相关分析、logistic多因素回归分析、交互作用分析。分析不同切点的BMI、WC、WHR作为暴露因素时高血压、高血糖及两者聚集性的相对危险度(RR)、归因危险度百分比(ARP)和人群归因危险度百分比(PARP)。
1)BMI、WC与血压、血糖的相关性优于WHR。2)经年龄、性别、职业、休闲体力活动、文化程度及糖尿病家族史校正后,结果显示BMI、WC、WHR均为重要的预测因素,相对重要性为BMI>WC>WHR。3)BMI、WC、WHR与高血压、高血糖存在增强交互作用,尤其是BMI与WC的交互作用。其纯归因交互作用百分比为5.95%~29.34%。4)BMI≥23、≥24、≥25时RR值约为2.5,提示暴露因素与疾病的关联程度为中高度有害。其ARP为0.580~0.623,PARP为0.259~0.425。男性WC≥85cm、女性WC≥80cm以及男性WC≥90cm、女性WC≥80cm时RR值为2.06~3.08,提示暴露因素与疾病的关联程度为中高度有害。其ARP为0.515~0.676,PARP为0.241~0.431。
鉴于我国暴露因素对疾病的有害程度、人群对超重肥胖的可接受性以及超重肥胖的防治尚处于起步阶段。BMI和WC预测高血压、高血糖的应用价值似乎优于WHR。建议以BMI作为肥胖指标,诊断切点为BMI≥24;以WC作为腹型肥胖指标,男性诊断切点建议为WC≥85cm,女性为WC≥80cm。