Bradley Patrick J.
Department of Otorhinolaryngology Head and Neck Surgery, University Hospital, Queens Medical Centre, Nottingham NG7 5EU, England.
Curr Infect Dis Rep. 2002 Jun;4(3):217-224. doi: 10.1007/s11908-002-0082-3.
Acute and chronic inflammatory diseases of the major and minor salivary glands constitute the most common clinical syndrome of salivary glands. During the past decade, the use of antibiotics along with fluid hydration and electrolyte management has almost eliminated the development of fulminating acute suppurative parotitis in hospital surgical patients. Although acute bacterial and viral sialadenitis persists, the clinical challenge has changed, with more focus on the chronic inflammatory group of diseases. The pathogenesis of the chronic salivary inflammatory disease spectrum has also changed, with the interplay between sialadenitis, sialectasia, and sialolithiasis. There also exists a heterogeneous group of disorders in chronic inflammatory sialadenitis, which include the group of specific and nonspecific granulomatous diseases.
大、小唾液腺的急慢性炎症性疾病构成了唾液腺最常见的临床综合征。在过去十年中,抗生素的使用以及液体水化和电解质管理几乎消除了医院手术患者暴发性急性化脓性腮腺炎的发生。尽管急性细菌性和病毒性涎腺炎仍然存在,但临床挑战已经改变,更多地集中在慢性炎症性疾病组。慢性唾液腺炎性疾病谱的发病机制也发生了变化,涎腺炎、涎腺扩张和涎石病之间相互影响。在慢性炎症性涎腺炎中还存在一组异质性疾病,包括特异性和非特异性肉芽肿性疾病。